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Description
  • Cílem práce bylo studium vztahů mezi radiálním a centrálním (karotickým) augmentačním indexem měřeným automatizovaným přístrojem za různých podmínek (podání NTG, cold-pressorický test) u dobrovolníků s širokým rozmezím věku a cévní tuhosti. Práce ukázala, že mezi radiálním a karotickým augmentačním indexem je těsný a lineární vztah a že lze automatizovaný rAI použít k odhadu centrálního tlakového profilu. (cs)
  • BACKGROUND: Peripheral wave reflection augments central blood pressure and contributes to cardiac load. This pressure augmentation is not quantifiable from brachial cuff pressure but can be determined from carotid pulsations using the augmentation index (AI). However, carotid tonometry is technically challenging and difficult to standardize in practice. We tested whether automated radial pressure analysis provides a viable alternative. METHODS AND RESULTS: Carotid and radial AI (cAI, rAI) were measured in 46 volunteers with a broad range of arterial properties. Data were assessed at rest, during a cold-pressor test, and following 0.4 mg of sublingual nitroglycerin. cAI correlated with rAI independent of age, mean blood pressure (BP), gender or body mass (cAI = 0.79 x rAI - 0.467, r = 0.81, P < 0.00001), with zero mean bias. There was individual variability in the prediction (difference of -4 +/- 23%), though 65% of the estimates fell within 15% of each other. Change in rAI and cAI with provocative
  • BACKGROUND: Peripheral wave reflection augments central blood pressure and contributes to cardiac load. This pressure augmentation is not quantifiable from brachial cuff pressure but can be determined from carotid pulsations using the augmentation index (AI). However, carotid tonometry is technically challenging and difficult to standardize in practice. We tested whether automated radial pressure analysis provides a viable alternative. METHODS AND RESULTS: Carotid and radial AI (cAI, rAI) were measured in 46 volunteers with a broad range of arterial properties. Data were assessed at rest, during a cold-pressor test, and following 0.4 mg of sublingual nitroglycerin. cAI correlated with rAI independent of age, mean blood pressure (BP), gender or body mass (cAI = 0.79 x rAI - 0.467, r = 0.81, P < 0.00001), with zero mean bias. There was individual variability in the prediction (difference of -4 +/- 23%), though 65% of the estimates fell within 15% of each other. Change in rAI and cAI with provocative (en)
Title
  • Estimation of central pressure augmentation using automated radial artery tonometry
  • Odhad centrální tlakové augmentace pomocí tonometrie radiální tepny (cs)
  • Estimation of central pressure augmentation using automated radial artery tonometry (en)
skos:prefLabel
  • Estimation of central pressure augmentation using automated radial artery tonometry
  • Odhad centrální tlakové augmentace pomocí tonometrie radiální tepny (cs)
  • Estimation of central pressure augmentation using automated radial artery tonometry (en)
skos:notation
  • RIV/00023001:_____/07:00000773!RIV08-MZ0-00023001
http://linked.open.../vavai/riv/strany
  • 1403-1409
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MZ0IKEM2005)
http://linked.open...iv/cisloPeriodika
  • 7
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 420469
http://linked.open...ai/riv/idVysledku
  • RIV/00023001:_____/07:00000773
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • artery; augmentation index; human; hypertension; non-invasive; pulse; tonometry (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [162CD54BD62A]
http://linked.open...i/riv/nazevZdroje
  • Journal of Hypertension
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 25
http://linked.open...iv/tvurceVysledku
  • Melenovský, Vojtěch
  • Kass, D. A.
  • Borlaug, B. A.
  • Kessler, K.
  • Fetics, B.
  • Shively, L.
http://linked.open...n/vavai/riv/zamer
issn
  • 0263-6352
number of pages
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