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rdf:type
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Description
| - citlivost vůči inzulinu, těžká hypotyreóza, substituční léčba hormonem štítné žlázy, euglykemický clamp (cs)
- We examined insulin sensitivity and secretion, together with the levels of selected glucoregulatory hormones, in 15 female patients with severe hypothyroidism (H) and during subsequent thyroid hormone replacement therapy (HRT) using the euglycaemic hyperinsulinaemic clamp technique. Insulin action, as evaluated by glucose disposal, the insulin sensitivity index, and fasting post-hepatic insulin delivery rate were established. The basal levels of insulin, C-peptide and counter-regulatory hormones were measured in basal condition. In H, glucose disposal (p-0.01), the insulin sensitivity index (p-0.01) and post-hepatic insulin delivery rate (p-0.05) were significantly lower than during HRT. No significant changes in the levels of fasting insulin and C-peptide were observed. The levels of counter-regulatory hormones in patients with H were significantly higher than during HRT (glucagon, p-0.05; epinephrine, p-0.01; cortisol, p-0.05; growth hormone, p-0.05). In H, an inverse correlation
- We examined insulin sensitivity and secretion, together with the levels of selected glucoregulatory hormones, in 15 female patients with severe hypothyroidism (H) and during subsequent thyroid hormone replacement therapy (HRT) using the euglycaemic hyperinsulinaemic clamp technique. Insulin action, as evaluated by glucose disposal, the insulin sensitivity index, and fasting post-hepatic insulin delivery rate were established. The basal levels of insulin, C-peptide and counter-regulatory hormones were measured in basal condition. In H, glucose disposal (p-0.01), the insulin sensitivity index (p-0.01) and post-hepatic insulin delivery rate (p-0.05) were significantly lower than during HRT. No significant changes in the levels of fasting insulin and C-peptide were observed. The levels of counter-regulatory hormones in patients with H were significantly higher than during HRT (glucagon, p-0.05; epinephrine, p-0.01; cortisol, p-0.05; growth hormone, p-0.05). In H, an inverse correlation (en)
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Title
| - Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy
- Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy (en)
- Citlivost na inzulin a kontraregulační hormony u hypothyroiditidy a během sbustituční léčby hormonem štítné žlázy (cs)
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skos:prefLabel
| - Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy
- Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy (en)
- Citlivost na inzulin a kontraregulační hormony u hypothyroiditidy a během sbustituční léčby hormonem štítné žlázy (cs)
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skos:notation
| - RIV/00023001:_____/05:00001311!RIV08-MZ0-00023001
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00023001:_____/05:00001311
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - diabetology; endocrinology (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Clinical chemistry and laboratory medicine
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Pelikánová, Terezie
- Vlček, P.
- Hill, M.
- Stanická, S.
- Zamrazil, V.
- Vondra, K.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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