About: Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice     Goto   Sponge   NotDistinct   Permalink

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Description
  • vazební kazety G5 a G8, játra, sekrece cholesterolu, myši (cs)
  • BACKGROUND/AIM: Mutations in genes encoding the ATP-binding cassette (ABC)-transporters ABCG5 and ABCG8 underlie sitosterolemia, which is characterized by elevated plasma levels of phytosterols due to increased intestinal absorption and impaired biliary secretion of sterols. The aim of our study was to correlate the expression levels of Abcg5 and Abcg8 to biliary cholesterol secretion in various (genetically-modified) mouse models.
  • BACKGROUND/AIM: Mutations in genes encoding the ATP-binding cassette (ABC)-transporters ABCG5 and ABCG8 underlie sitosterolemia, which is characterized by elevated plasma levels of phytosterols due to increased intestinal absorption and impaired biliary secretion of sterols. The aim of our study was to correlate the expression levels of Abcg5 and Abcg8 to biliary cholesterol secretion in various (genetically-modified) mouse models. (en)
Title
  • Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice
  • Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice (en)
  • Vztah mezi expresí transportérů ATP-vazebných kazet G5 a G8 v játrech a sekrecí cholesterolu ve žluči u myší (cs)
skos:prefLabel
  • Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice
  • Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice (en)
  • Vztah mezi expresí transportérů ATP-vazebných kazet G5 a G8 v játrech a sekrecí cholesterolu ve žluči u myší (cs)
skos:notation
  • RIV/00023001:_____/03:00000961!RIV08-MZ0-00023001
http://linked.open.../vavai/riv/strany
  • 710-716
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • N
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 625142
http://linked.open...ai/riv/idVysledku
  • RIV/00023001:_____/03:00000961
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Abcg5; Abcg8; Biliary cholesterol secretion; Real-time polymerase chain reaction (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [9F0A79616A03]
http://linked.open...i/riv/nazevZdroje
  • Journal of Hepatology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 38
http://linked.open...iv/tvurceVysledku
  • Jirsa, Milan
  • Schaap, F. G.
  • Kosters, A.
  • Frijters, R. J. J. M.
  • Ottenhoff, R.
  • Plösch, T.
  • Vink, E.
issn
  • 0168-8278
number of pages
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