About: Activation of murine RNase L by isopolar 2 '-phosphonate analogues of 2 ',5 ' oligoadenylates     Goto   Sponge   NotDistinct   Permalink

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Description
  • Abychom zjistili vliv methyléhového můstku inzertovaného do internukleotidové vazby modifikovaných oligoadenylátů na affinitu a aktivační schopnosti vůči RNase L, syntetizovali jsme serii 2'-fosfonátových trimerů a tetramerů za použití monomerních jednotek. (cs)
  • To determine the influence of methylene group insertion in the internucleotide linkage on the binding process of 2', 5'-oligoadenylates to RNase L, a series of 2'-phosphonate-modified trimers and tetramers were synthesized from appropriate monomeric units and evaluated for their ability to bind to murine RNase L.
  • To determine the influence of methylene group insertion in the internucleotide linkage on the binding process of 2', 5'-oligoadenylates to RNase L, a series of 2'-phosphonate-modified trimers and tetramers were synthesized from appropriate monomeric units and evaluated for their ability to bind to murine RNase L. (en)
Title
  • Activation of murine RNase L by isopolar 2 '-phosphonate analogues of 2 ',5 ' oligoadenylates
  • Activation of murine RNase L by isopolar 2 '-phosphonate analogues of 2 ',5 ' oligoadenylates (en)
  • Activace myší RNasy L isopolárními 2 '-fosfonátovými analogy 2 ',5 ' oligoadenylátů (cs)
skos:prefLabel
  • Activation of murine RNase L by isopolar 2 '-phosphonate analogues of 2 ',5 ' oligoadenylates
  • Activation of murine RNase L by isopolar 2 '-phosphonate analogues of 2 ',5 ' oligoadenylates (en)
  • Activace myší RNasy L isopolárními 2 '-fosfonátovými analogy 2 ',5 ' oligoadenylátů (cs)
skos:notation
  • RIV/61388963:_____/06:00040355!RIV07-AV0-61388963
http://linked.open.../vavai/riv/strany
  • 3955;3962
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GP203/04/P273), P(IAA4055101), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika
  • 13
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 464066
http://linked.open...ai/riv/idVysledku
  • RIV/61388963:_____/06:00040355
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • oligoadenylates; phosphonates; RNase L (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [D82F811399FA]
http://linked.open...i/riv/nazevZdroje
  • Journal of Medicinal Chemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 49
http://linked.open...iv/tvurceVysledku
  • Buděšínský, Miloš
  • Rosenberg, Ivan
  • Jiráček, Jiří
  • Masojídková, Milena
  • Páv, Ondřej
  • Snášel, Jan
  • Pressová, Martina
  • Protivínská, Eva
  • Collinsová, Michaela
http://linked.open...n/vavai/riv/zamer
issn
  • 0022-2623
number of pages
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