About: Synthesis of N9- and N7-[2-hydroxy-3-(phosphonomethoxy)-propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds

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About: Synthesis of N9- and N7-[2-hydroxy-3-(phosphonomethoxy)-propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Reakce diethylesteru [(oxiranylmethoxy)methyl]fosfonové kyseliny s 6-chlorpurinem a 2-amino-6-chlorpurinem poskytla odpovídající 9-[2-hydroxy-3-(fosfonomethoxy)propyl]puriny, jejichž reakcí s aminy a následným odstraněním esterových skupin bromtrimethylsilanem byly připraveny N6-substituované 2-hydroxy-3-(fosfonomethoxy)propyl adeniny a diaminopuriny (cs) Reaction of diethyl [(oxiranylmethoxy)methyl]phosphonate with 6-chloropurine and 2-amino-6-chloropurine gave corresponding 9-[2-hydroxy-3-(phosphonomethoxy)propyl]purines which were treated with amines and subsequently deprotected with bromotrimethylsilane to give N6-substituted 2-hydroxy-3-(phosphonomethoxy)propyl adenines and diaminopurines Reaction of diethyl [(oxiranylmethoxy)methyl]phosphonate with 6-chloropurine and 2-amino-6-chloropurine gave corresponding 9-[2-hydroxy-3-(phosphonomethoxy)propyl]purines which were treated with amines and subsequently deprotected with bromotrimethylsilane to give N6-substituted 2-hydroxy-3-(phosphonomethoxy)propyl adenines and diaminopurines (en)
Title	Synthesis of N9- and N7-[2-hydroxy-3-(phosphonomethoxy)-propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds Syntéza N9- and N7-[2-hydroxy-3-(fosfonomethoxy)propyl]derivátů N6-substituovaných adeninů, 2,6-diaminopurinů a příbuzných sloučenin (cs) Synthesis of N9- and N7-[2-hydroxy-3-(phosphonomethoxy)-propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds (en)
skos:prefLabel	Synthesis of N9- and N7-[2-hydroxy-3-(phosphonomethoxy)-propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds Syntéza N9- and N7-[2-hydroxy-3-(fosfonomethoxy)propyl]derivátů N6-substituovaných adeninů, 2,6-diaminopurinů a příbuzných sloučenin (cs) Synthesis of N9- and N7-[2-hydroxy-3-(phosphonomethoxy)-propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds (en)
skos:notation	RIV/61388963:_____/04:00102433!RIV/2005/AV0/A57005/N
http://linked.open.../vavai/riv/strany	1889;1913
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IBS4055109), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Krečmerová, Marcela Holý, Antonín Masojídková, Milena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	589359
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/04:00102433
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	acyclic nucleotide analogues;phosphonates;purines (en)
http://linked.open.../riv/klicoveSlovo	phosphonates purines acyclic nucleotide analogues
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[DE4E4186E02B]
http://linked.open...i/riv/nazevZdroje	Collection of Czechoslovak Chemical Communications
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Acyclic nucleoside phosponates with antineoplastic activity
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	69
http://linked.open...iv/tvurceVysledku	Holý, Antonín Krečmerová, Marcela Masojídková, Milena
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0010-0765
number of pages	25 (xsd:int)

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