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  • High performance liquid chromatography (HPLC) in tandem with mass spectrometry (MS) is widely used in chemical and biochemical analysis of the content of measured samples, especially in so-called omics science. Currently, there are methods for processing and analyzing the measured data sets from proteomics as well as metabolomics. However, only some of the problems of processing and analyzing tasks have been compensated for, and even in these cases, they have only been considered independently. Therefore, the current state of data handling is studied. This review describes the currently available methods and techniques commonly used in HPLC-MS for processing and analysis. All the main types of processing and most popular methods are mentioned. However, any overview will fail to be exhaustive. Therefore, some additional literature that goes into further detail is recommended. The review itself reveals some of the important shortcomings of the current state of the art. A list of relevant subtopics relating to different research focuses is provided in the conclusion.
  • High performance liquid chromatography (HPLC) in tandem with mass spectrometry (MS) is widely used in chemical and biochemical analysis of the content of measured samples, especially in so-called omics science. Currently, there are methods for processing and analyzing the measured data sets from proteomics as well as metabolomics. However, only some of the problems of processing and analyzing tasks have been compensated for, and even in these cases, they have only been considered independently. Therefore, the current state of data handling is studied. This review describes the currently available methods and techniques commonly used in HPLC-MS for processing and analysis. All the main types of processing and most popular methods are mentioned. However, any overview will fail to be exhaustive. Therefore, some additional literature that goes into further detail is recommended. The review itself reveals some of the important shortcomings of the current state of the art. A list of relevant subtopics relating to different research focuses is provided in the conclusion. (en)
Title
  • Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics
  • Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics (en)
skos:prefLabel
  • Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics
  • Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics (en)
skos:notation
  • RIV/60076658:12520/12:43884034!RIV13-MSM-12520___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED2.1.00/01.0024), Z(MSM6007665808)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 129275
http://linked.open...ai/riv/idVysledku
  • RIV/60076658:12520/12:43884034
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • time alignment; mass spectrometry; liquid chromatography; Feature detection (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • AE - Stát Spojené arabské emiráty
http://linked.open...ontrolniKodProRIV
  • [2343E46EC5D7]
http://linked.open...i/riv/nazevZdroje
  • CURRENT PROTEOMICS
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 9
http://linked.open...iv/tvurceVysledku
  • Urban, Jan
  • Vaněk, Jan
  • Štys, Dalibor
http://linked.open...ain/vavai/riv/wos
  • 000305654000002
http://linked.open...n/vavai/riv/zamer
issn
  • 1570-1646
number of pages
http://bibframe.org/vocab/doi
  • 10.2174/157016412800786248
http://localhost/t...ganizacniJednotka
  • 12520
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