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rdf:type
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Description
| - The chronic toxic effects of carbamazepine (CBZ) on rainbow trout were investigated. Fish were exposed at sublethal concentrations of CBZ (1.0 μg.l-1, 0.2 mg l-1 and 2.0 mg.l-1) for 42 days. Compared with the control, there was a significant lower (P < 0.05) condition factor in fish exposed at the highest concentration of CBZ (2.0 mg.l-1), but the hepatosomatic indices in all groups were not significant changes. At lower CBZ concentration (1.0 μg.l-1, 0.2 mg.l-1), the antioxidant enzyme activities were induced slightly, except catalase, while at the highest concentration (2.0 mg.l-1) oxidative stress was apparent as reflected by the significant higher lipid peroxidation and protein carbonyls in the fish muscle, associated with a significant inhibition of antioxidant enzymes activities. Moreover, energy metabolic parameters (RNA-DNA ratio, Na+-K+-ATPase) were significantly inhibited in muscle of the fish exposed at the highest concentration (2.0 mg.l-1), compared with the control.
- The chronic toxic effects of carbamazepine (CBZ) on rainbow trout were investigated. Fish were exposed at sublethal concentrations of CBZ (1.0 μg.l-1, 0.2 mg l-1 and 2.0 mg.l-1) for 42 days. Compared with the control, there was a significant lower (P < 0.05) condition factor in fish exposed at the highest concentration of CBZ (2.0 mg.l-1), but the hepatosomatic indices in all groups were not significant changes. At lower CBZ concentration (1.0 μg.l-1, 0.2 mg.l-1), the antioxidant enzyme activities were induced slightly, except catalase, while at the highest concentration (2.0 mg.l-1) oxidative stress was apparent as reflected by the significant higher lipid peroxidation and protein carbonyls in the fish muscle, associated with a significant inhibition of antioxidant enzymes activities. Moreover, energy metabolic parameters (RNA-DNA ratio, Na+-K+-ATPase) were significantly inhibited in muscle of the fish exposed at the highest concentration (2.0 mg.l-1), compared with the control. (en)
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Title
| - Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine
- Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine (en)
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skos:prefLabel
| - Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine
- Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine (en)
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skos:notation
| - RIV/60076658:12520/10:00011403!RIV11-MZP-12520___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(SP/2E7/229/07), Z(MSM6007665809)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60076658:12520/10:00011403
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Fish; residual pharmaceutical; oxidative stress; condition factor; hepatosomatic index; RNA-DNA ratio; Na+-K+-ATPase (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Applied Toxicology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Grabic, Roman
- Li, Zhihua
- Máchová, Jana
- Randák, Tomáš
- Velíšek, Josef
- Žlábek, Vladimír
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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