About: ELECTROCHEMICAL STUDY OF SHORT CYTOSINE OLIGONUCLEOTIDES

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cytosine-rich oligodeoxynucleotides (C-rich ODNs) play diverse roles in the regulation of protein expression at both transcriptional and translational levels. A repetitive C sequence can be responsible for some diseases. It is commonly known that C-rich ODNs form the stable i-motif structure, interesting due to a crucial role in the process of genetic information transfer. The aim of this contribution is to find out the relationship between the structure of homo-ODNs in buffered solutions with the same ionic strength (I = 0.18 M) but with a different number of cytosines (dCx; x = 3, 4, 5, 6, 9). Using linear sweep voltammetry (LSV) and elimination voltammetry with linear scan (EVLS), electrochemical reduction signals studied on a mercury electrode reflect the conformation changes of the C-rich ODN chain. Cytosine-rich oligodeoxynucleotides (C-rich ODNs) play diverse roles in the regulation of protein expression at both transcriptional and translational levels. A repetitive C sequence can be responsible for some diseases. It is commonly known that C-rich ODNs form the stable i-motif structure, interesting due to a crucial role in the process of genetic information transfer. The aim of this contribution is to find out the relationship between the structure of homo-ODNs in buffered solutions with the same ionic strength (I = 0.18 M) but with a different number of cytosines (dCx; x = 3, 4, 5, 6, 9). Using linear sweep voltammetry (LSV) and elimination voltammetry with linear scan (EVLS), electrochemical reduction signals studied on a mercury electrode reflect the conformation changes of the C-rich ODN chain. (en)
Title	ELECTROCHEMICAL STUDY OF SHORT CYTOSINE OLIGONUCLEOTIDES ELECTROCHEMICAL STUDY OF SHORT CYTOSINE OLIGONUCLEOTIDES (en)
skos:prefLabel	ELECTROCHEMICAL STUDY OF SHORT CYTOSINE OLIGONUCLEOTIDES ELECTROCHEMICAL STUDY OF SHORT CYTOSINE OLIGONUCLEOTIDES (en)
skos:notation	RIV/00216224:14740/12:00057421!RIV13-GA0-14740___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(GD106/09/H035)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Balcarová, Zdeňka Trnková, Libuše Pilařová, Iveta Gurecký, Libor
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	133888
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/12:00057421
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cytosine; oligonucleotides; cyclic voltammetry; elimination voltammetry (en)
http://linked.open.../riv/klicoveSlovo	cyclic voltammetry cytosine oligonucleotides elimination voltammetry
http://linked.open...ontrolniKodProRIV	[B55690131D6C]
http://linked.open...v/mistoKonaniAkce	Brno
http://linked.open...i/riv/mistoVydani	Brno
http://linked.open...i/riv/nazevZdroje	XII. Pracovní setkání fyzikálních chemiků a elektrochemiků
http://linked.open...in/vavai/riv/obor	CF
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology Multiscale design of advanced materials
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Balcarová, Zdeňka Trnková, Libuše Pilařová, Iveta Gurecký, Libor
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2012-01-01 (xsd:date)
number of pages	2 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Mendelova zemědělská a lesnická univerzita v Brně
https://schema.org/isbn	9788073756185
http://localhost/t...ganizacniJednotka	14740

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