About: Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method

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About: Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A simple and sensitive method was developed to separate the carcinogenic polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), and six of its oxidation metabolites generated by rat hepatic microsomes enriched with cytochrome P450 (CYP) 1A1, by high pressure liquid chromatography (HPLC). A simple and sensitive method was developed to separate the carcinogenic polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), and six of its oxidation metabolites generated by rat hepatic microsomes enriched with cytochrome P450 (CYP) 1A1, by high pressure liquid chromatography (HPLC). (en)
Title	Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method (en)
skos:prefLabel	Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method (en)
skos:notation	RIV/00216208:11310/09:10000166!RIV11-GA0-11310___
http://linked.open...avai/riv/aktivita	I P S Z
http://linked.open...avai/riv/aktivity	I, P(1M0505), P(GA303/09/0472), P(GD305/09/H008), S, Z(MSM0021620808)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Svášková, Dagmar Moserová, Michaela Kotrbová, Věra Stiborová, Marie Šulc, Miroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	302822
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/09:10000166
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	optimization the method; high pressure liquid chromatography; hepatic microsomes; cytochrome P450 (CYP) 1A1; rat; benzo[a]pyrene metabolites (en)
http://linked.open.../riv/klicoveSlovo	hepatic microsomes benzo[a]pyrene metabolites cytochrome P450 (CYP) 1A1 high pressure liquid chromatography optimization the method rat
http://linked.open...odStatuVydavatele	SK - Slovenská republika
http://linked.open...ontrolniKodProRIV	[5419201108B5]
http://linked.open...i/riv/nazevZdroje	Interdisciplinary Toxicology
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Center of targeted therapeutic drugs Study on participation of biotransformation enzymes in development of renal injury and urothelial cancer mediated by aristolochic acid Preparation, biotransformation, and optimalization of compounds with antitumor and antimicrobial effects
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	2
http://linked.open...iv/tvurceVysledku	Frei, Eva Stiborová, Marie Šulc, Miroslav Kotrbová, Věra Moserová, Michaela Svášková, Dagmar
http://linked.open...n/vavai/riv/zamer	Molekulárně biologické, genetické a epigenetické aspekty vzniku a rozvoje modelových tumorů dospělého věku. Význam pro epidemiologii, časnou diagnostiku a léčbu
issn	1337-6853
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	11310

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