About: Renal epithelioid angiomyolipoma - a close mimic of renal cell carcinoma: Report of a case and review of the literature     Goto   Sponge   NotDistinct   Permalink

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Description
  • The epithelioid variant of angiomyolipoma (EAML) is a rare tumor of unpredictable behavior that is composed of epitheliold, spindle, and giant cells and contains no or only a minimal amount of lipomatous tissue. The picture can lead to an erroneous diagnosis of renal cell carcinoma or sarcoma. We report on a case of EAML in the kidney of a 47-year-old female without any signs of tuberous sclerosis and review the literature. Grossly, a well-demarcated, spheroid, largely hemorrhagic tumor measuring 4.2 cm in diameter occupied the central third of the kidney. Histologically, it was solid, highly cellular, with occasional microcysts, composed of medium to large epithelioid cells with clear or oxyphilic cytoplasm, short spindle cells, and numerous giant multinucleated cells. After extensive sampling, adult-appearing fat tissue was found to present as rare foci of microscopic dimensions. Immunohistochemically, the tumor cells showed positive reactions with antibodies against HMB-45, melan A, CD-68, muscle-s
  • The epithelioid variant of angiomyolipoma (EAML) is a rare tumor of unpredictable behavior that is composed of epitheliold, spindle, and giant cells and contains no or only a minimal amount of lipomatous tissue. The picture can lead to an erroneous diagnosis of renal cell carcinoma or sarcoma. We report on a case of EAML in the kidney of a 47-year-old female without any signs of tuberous sclerosis and review the literature. Grossly, a well-demarcated, spheroid, largely hemorrhagic tumor measuring 4.2 cm in diameter occupied the central third of the kidney. Histologically, it was solid, highly cellular, with occasional microcysts, composed of medium to large epithelioid cells with clear or oxyphilic cytoplasm, short spindle cells, and numerous giant multinucleated cells. After extensive sampling, adult-appearing fat tissue was found to present as rare foci of microscopic dimensions. Immunohistochemically, the tumor cells showed positive reactions with antibodies against HMB-45, melan A, CD-68, muscle-s (en)
Title
  • Renal epithelioid angiomyolipoma - a close mimic of renal cell carcinoma: Report of a case and review of the literature
  • Renal epithelioid angiomyolipoma - a close mimic of renal cell carcinoma: Report of a case and review of the literature (en)
skos:prefLabel
  • Renal epithelioid angiomyolipoma - a close mimic of renal cell carcinoma: Report of a case and review of the literature
  • Renal epithelioid angiomyolipoma - a close mimic of renal cell carcinoma: Report of a case and review of the literature (en)
skos:notation
  • RIV/00216208:11120/05:00003046!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S, V
http://linked.open...iv/cisloPeriodika
  • 11-12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 540759
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/05:00003046
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • kidney; epithelioid angiomyolipoma; histology; immunophenotype; prognosis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [702DC86E24A5]
http://linked.open...i/riv/nazevZdroje
  • Pathology Research and Practice
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 200
http://linked.open...iv/tvurceVysledku
  • Švec, Alexandr
  • Velenská, Zuzana
http://linked.open...ain/vavai/riv/wos
  • 000227906400017
issn
  • 0344-0338
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.prp.2004.09.004
http://localhost/t...ganizacniJednotka
  • 11120
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