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rdf:type
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Description
| - We confirmed co-localization of four breakpoints: 5q15, 5q33, 7q21.11 7q32.3 and FS in MDS patients. Their roles in clonal transformation are not yet fully characterized. However, tumor-suppressor genes and/or oncogenes are predicted to reside in these loci. Further microarray analyses of the affected chromosomal regions in combination with molecular-cytogenetic approaches will help to elucidate the degree of correlation with fragile sites.
- We confirmed co-localization of four breakpoints: 5q15, 5q33, 7q21.11 7q32.3 and FS in MDS patients. Their roles in clonal transformation are not yet fully characterized. However, tumor-suppressor genes and/or oncogenes are predicted to reside in these loci. Further microarray analyses of the affected chromosomal regions in combination with molecular-cytogenetic approaches will help to elucidate the degree of correlation with fragile sites. (en)
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Title
| - Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites
- Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites (en)
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skos:prefLabel
| - Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites
- Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites (en)
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skos:notation
| - RIV/00064173:_____/12:#0000384!RIV14-MZ0-00064173
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(LC535), P(OC10043), V, Z(MSM0021620808), Z(MZ0UHKT2005), Z(MZ0VFN2005)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00064173:_____/12:#0000384
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - chromosomal breakpoints; myelodysplastic syndrome (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.leukres.2012.02.006
|