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Description
  • Tento přehledný článek shrnuje nedávné pokroky v oblasti vývoje protinádorově účinných platinových sloučenin. Podporuje také názor, podle kterého (i´) existuje korelace mezi protinádorovou aktivitou platinových sloučenin a jejich schopností vyvolávat určitý typ konformačních a jiných změn v DNA; (ii) tato korelace může být využita pro jednoduché testování a vyhledávání nových, protinádorově účinných platinových komplexů. (cs)
  • The present review summarizes recent advances in the area of development of antitumor platinum drugs. It also provides a strong support for the view that (i) there is a correlation between antitumor activity of platinum compounds and their capacility to induce in DNA a certain sort of conformational and other alterations; (ii) this correlation may be exploited for simple screening of new platinum complexes for antitumor activity in the search for new antitumor platinum drugs.
  • The present review summarizes recent advances in the area of development of antitumor platinum drugs. It also provides a strong support for the view that (i) there is a correlation between antitumor activity of platinum compounds and their capacility to induce in DNA a certain sort of conformational and other alterations; (ii) this correlation may be exploited for simple screening of new platinum complexes for antitumor activity in the search for new antitumor platinum drugs. (en)
Title
  • Metal compounds in cancer chemotherapy
  • Kovové sloučeniny v chemoterapii rakoviny (cs)
  • Metal compounds in cancer chemotherapy (en)
skos:prefLabel
  • Metal compounds in cancer chemotherapy
  • Kovové sloučeniny v chemoterapii rakoviny (cs)
  • Metal compounds in cancer chemotherapy (en)
skos:notation
  • RIV/68081707:_____/05:00023937!RIV06-AV0-68081707
http://linked.open.../vavai/riv/strany
  • 187;218
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA305/05/2030), P(NR8562), Z(AV0Z50040507)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 529653
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/05:00023937
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • DNA; platinum; antitumor (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [AA8D03DA345A]
http://linked.open...i/riv/mistoVydani
  • Trivandrum
http://linked.open...i/riv/nazevZdroje
  • -
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Brabec, Viktor
  • Kašpárková, Jana
http://linked.open...n/vavai/riv/zamer
number of pages
http://purl.org/ne...btex#hasPublisher
  • Research Signpost
https://schema.org/isbn
  • 81-7736-277-1
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