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  • Current development of miniature analytical instruments for detecting heavy metals in various samples is very dynamic. The most interesting representatives of these instruments are biosensors, which combine the physico-chemical transducer with biological components. Biosensors operate on different principles and their preparation can lead to the acquisition of tools with high sensitivity and selectivity against individual heavy metal ions or their mixtures. In this paper, various types of biosensors divided according to their biological components for the detection of heavy metals ions are discussed. Generally, biosensors for heavy metals detection can be divided into two groups, based on their biological part: i) protein biosensors and ii) biosensors based on nucleic acids. Biosensors using nucleic acids represent new and quickly developing branch. Protein biosensors can be divided into enzymatic and affinity ones, while enzymatic biosensors are based on activation or inhibition enzymes activity the affinity biosensors use specific antibodies. Affinity biosensors using immunodetection belong to other method for metal ion determination, which - in comparing with traditional detection methods - brings certain advantages, such as high sensitivity and selectivity. They are theoretically useful for other metal complexes, where the antibody can be prepared. Biosensors belong to the most powerful bioanalytical tools and represent future in development of instruments which can be used in medicine and pharmaceutical research, environment and BioDefence techniques and in monitoring of food quality and safety.
  • Current development of miniature analytical instruments for detecting heavy metals in various samples is very dynamic. The most interesting representatives of these instruments are biosensors, which combine the physico-chemical transducer with biological components. Biosensors operate on different principles and their preparation can lead to the acquisition of tools with high sensitivity and selectivity against individual heavy metal ions or their mixtures. In this paper, various types of biosensors divided according to their biological components for the detection of heavy metals ions are discussed. Generally, biosensors for heavy metals detection can be divided into two groups, based on their biological part: i) protein biosensors and ii) biosensors based on nucleic acids. Biosensors using nucleic acids represent new and quickly developing branch. Protein biosensors can be divided into enzymatic and affinity ones, while enzymatic biosensors are based on activation or inhibition enzymes activity the affinity biosensors use specific antibodies. Affinity biosensors using immunodetection belong to other method for metal ion determination, which - in comparing with traditional detection methods - brings certain advantages, such as high sensitivity and selectivity. They are theoretically useful for other metal complexes, where the antibody can be prepared. Biosensors belong to the most powerful bioanalytical tools and represent future in development of instruments which can be used in medicine and pharmaceutical research, environment and BioDefence techniques and in monitoring of food quality and safety. (en)
Title
  • Biosensors for detection of heavy metals
  • Biosensors for detection of heavy metals (en)
skos:prefLabel
  • Biosensors for detection of heavy metals
  • Biosensors for detection of heavy metals (en)
skos:notation
  • RIV/62156489:43210/12:00198837!RIV13-GA0-43210___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA102/08/1546), P(KAN208130801)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 125184
http://linked.open...ai/riv/idVysledku
  • RIV/62156489:43210/12:00198837
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • biosensors; detection; heavy metals (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [5C0BA42327CE]
http://linked.open...i/riv/mistoVydani
  • London, UK
http://linked.open...vEdiceCisloSvazku
  • 1
http://linked.open...i/riv/nazevZdroje
  • Biosensors and Environmental Health
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Adam, Vojtěch
  • Hubálek, Jaromír
  • Kizek, René
  • Trnková, Libuše
  • Šobrová, Pavlína
number of pages
http://purl.org/ne...btex#hasPublisher
  • CRC Press
https://schema.org/isbn
  • 978-1-57808-735-8
http://localhost/t...ganizacniJednotka
  • 43210
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