About: Electrochemistry of metallothioneins

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Metallothioneins (MT) are a family of ubiquitous, biologically interesting proteins which have been isolated and studied in a wide variety of organisms, including prokaryotes, plants, invertebrates and vertebrates. Due to the property of MT being metal-inducible and, also, due to their high affinity to metal ions, homeostasis of heavy metal levels is probably their most important biological function. In addition, MT are involved in other important biochemical pathways including scavenging of reactive oxygen species, activation of transcription factors or participation in carcinogenesis. Detection and quantification of MT is not simple due to the high content of cysteine and relatively low molecular mass. These proteins can be detected very sensitively by electrochemical methods. Moreover, MT can be used as a part of biosensors. Metallothioneins (MT) are a family of ubiquitous, biologically interesting proteins which have been isolated and studied in a wide variety of organisms, including prokaryotes, plants, invertebrates and vertebrates. Due to the property of MT being metal-inducible and, also, due to their high affinity to metal ions, homeostasis of heavy metal levels is probably their most important biological function. In addition, MT are involved in other important biochemical pathways including scavenging of reactive oxygen species, activation of transcription factors or participation in carcinogenesis. Detection and quantification of MT is not simple due to the high content of cysteine and relatively low molecular mass. These proteins can be detected very sensitively by electrochemical methods. Moreover, MT can be used as a part of biosensors. (en)
Title	Electrochemistry of metallothioneins Electrochemistry of metallothioneins (en)
skos:prefLabel	Electrochemistry of metallothioneins Electrochemistry of metallothioneins (en)
skos:notation	RIV/62156489:43210/11:00173752!RIV12-AV0-43210___
http://linked.open...avai/predkladatel	Agronomická fakulta
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(IAA401990701)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Majzlík, Petr Blaštík, Ondřej Petrlová, Jitka Trnková, Libuše Adam, Vojtěch Kizek, René Šobrová, Pavlína
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mendelova univerzita v Brně / Agronomická fakulta
http://linked.open...dnocenehoVysledku	197051
http://linked.open...ai/riv/idVysledku	RIV/62156489:43210/11:00173752
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	protein; elektrochemistry; biological function (en)
http://linked.open.../riv/klicoveSlovo	protein biological function elektrochemistry
http://linked.open...ontrolniKodProRIV	[5665FCCF0893]
http://linked.open...v/mistoKonaniAkce	MENDELU
http://linked.open...i/riv/mistoVydani	Brno
http://linked.open...i/riv/nazevZdroje	XI. pracovní setkání fyzikálních chemiků a elektrochemiků
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of binding of platinum cytostatics to DNA structure; Influence of metallothionein
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Kizek, René Majzlík, Petr Trnková, Libuše Šobrová, Pavlína Blaštík, Ondřej Fabrik, Ivo Petrlová, Jitka
http://linked.open...vavai/riv/typAkce	CST - Celostátní
http://linked.open.../riv/zahajeniAkce	2011-01-01 (xsd:date)
number of pages	5 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Mendelova zemědělská a lesnická univerzita v Brně
https://schema.org/isbn	978-80-7375-514-0
http://localhost/t...ganizacniJednotka	43210

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