About: Biochemical profile of effect of deoxynivalenol supplemented by mouldy cereals on rats

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aims of this thesis consisted of investigating the impact mouldy grain contaminated with deoxynivalenol (DON) on the health status of rats and their ability to resist oxidative stress. Rats were 28 days feeding of diet supplemented with DON and others (organic and inorganic zinc, the addition of vitamins and mycosorb). Among the factors determining the levels of defences include peptides and proteins (glutathione, metallothionein (MT)). The highest concentration of MT was found in the tissues providing detoxification of xenobiotics, such as kidney (6.69 +/- 0.05 microg/ml) and liver (6.06 +/- 0.05 microg/ml). Half concentration was detected in heart, brain, testes and muscle (app. 3.0 microg/ml). In conclusion, the MT may play an important role in the detoxification of mycotoxins. Its role is not fully understood, but this protein is most likely associated with the redistribution of ions important for transcription factors and its interaction with reactive oxygen species that can form mycotoxins. The aims of this thesis consisted of investigating the impact mouldy grain contaminated with deoxynivalenol (DON) on the health status of rats and their ability to resist oxidative stress. Rats were 28 days feeding of diet supplemented with DON and others (organic and inorganic zinc, the addition of vitamins and mycosorb). Among the factors determining the levels of defences include peptides and proteins (glutathione, metallothionein (MT)). The highest concentration of MT was found in the tissues providing detoxification of xenobiotics, such as kidney (6.69 +/- 0.05 microg/ml) and liver (6.06 +/- 0.05 microg/ml). Half concentration was detected in heart, brain, testes and muscle (app. 3.0 microg/ml). In conclusion, the MT may play an important role in the detoxification of mycotoxins. Its role is not fully understood, but this protein is most likely associated with the redistribution of ions important for transcription factors and its interaction with reactive oxygen species that can form mycotoxins. (en)
Title	Biochemical profile of effect of deoxynivalenol supplemented by mouldy cereals on rats Biochemical profile of effect of deoxynivalenol supplemented by mouldy cereals on rats (en)
skos:prefLabel	Biochemical profile of effect of deoxynivalenol supplemented by mouldy cereals on rats Biochemical profile of effect of deoxynivalenol supplemented by mouldy cereals on rats (en)
skos:notation	RIV/62156489:43210/10:00166775!RIV12-GA0-43210___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(GP301/09/P436), S
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Křížková, Soňa Vašátková, Anna Zeman, Ladislav Adam, Vojtěch Kizek, René Šobrová, Pavlína
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mendelova univerzita v Brně / Agronomická fakulta
http://linked.open...dnocenehoVysledku	248829
http://linked.open...ai/riv/idVysledku	RIV/62156489:43210/10:00166775
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mouldy cereals; deoxynivalenol; rat (en)
http://linked.open.../riv/klicoveSlovo	rat deoxynivalenol mouldy cereals
http://linked.open...ontrolniKodProRIV	[51AB29894A5B]
http://linked.open...v/mistoKonaniAkce	Brno
http://linked.open...i/riv/mistoVydani	Brno
http://linked.open...i/riv/nazevZdroje	MendelNet 2010 Proceedings of International Ph.D. Students Conference
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Metallothionein analysis in prostate carcinoma at DNA, RNA and protein level.
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Kizek, René Křížková, Soňa Zeman, Ladislav Šobrová, Pavlína Vašátková, Anna
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2000-01-01 (xsd:date)
number of pages	7 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Mendelova zemědělská a lesnická univerzita v Brně
https://schema.org/isbn	978-80-7375-453-2
http://localhost/t...ganizacniJednotka	43210

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