About: KRAS NF-jB is involved in the development of zinc resistance and reduced curability in prostate cancer

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About: KRAS NF-jB is involved in the development of zinc resistance and reduced curability in prostate cancer Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Zinc(II) ions are important components of many proteins and are involved in numerous cellular processes such as apoptosis or drug resistance. Prostate cancer has a unique relationship with zinc(II) ions. However, the relationship was examined only in short-term zinc(II) treatments. Therefore, the aim of this study was to create zinc-resistant prostatic cell lines at various stages of the disease (22Rv1 and PC-3) and a normal prostate epithelium (PNT1A) using a long-term zinc exposure. Zinc(II) ions are important components of many proteins and are involved in numerous cellular processes such as apoptosis or drug resistance. Prostate cancer has a unique relationship with zinc(II) ions. However, the relationship was examined only in short-term zinc(II) treatments. Therefore, the aim of this study was to create zinc-resistant prostatic cell lines at various stages of the disease (22Rv1 and PC-3) and a normal prostate epithelium (PNT1A) using a long-term zinc exposure. (en)
Title	KRAS NF-jB is involved in the development of zinc resistance and reduced curability in prostate cancer KRAS NF-jB is involved in the development of zinc resistance and reduced curability in prostate cancer (en)
skos:prefLabel	KRAS NF-jB is involved in the development of zinc resistance and reduced curability in prostate cancer KRAS NF-jB is involved in the development of zinc resistance and reduced curability in prostate cancer (en)
skos:notation	RIV/00216305:26620/14:PU111705!RIV15-MSM-26620___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Raudenská, Martina Gumulec, Jaromír Babula, Petr Adam, Vojtěch Masařík, Michal Kizek, René
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	25133
http://linked.open...ai/riv/idVysledku	RIV/00216305:26620/14:PU111705
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	CITRATE METABOLISM, EPITHELIAL-CELLS, CARCINOMA-CELLS, DNA-DAMAGE, T-ANTIGEN, EXPRESSION, METALLOTHIONEIN, TRANSPORTER, APOPTOSIS, GENES (en)
http://linked.open.../riv/klicoveSlovo	CARCINOMA-CELLS CITRATE METABOLISM METALLOTHIONEIN T-ANTIGEN TRANSPORTER APOPTOSIS EXPRESSION EPITHELIAL-CELLS GENES DNA-DAMAGE
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[77905DF941A0]
http://linked.open...i/riv/nazevZdroje	METALLOMICS
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	6
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Babula, Petr Gumulec, Jaromír Kizek, René Masařík, Michal Sztalmachová, Markéta Holubová, Monika Raudenská, Martina Axmanová, Martina
issn	1756-5901
number of pages	14 (xsd:int)
http://localhost/t...ganizacniJednotka	26620

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