About: MONITORING OF DNA-DOXORUBICIN INTERACTIONS BY ELECTROCHEMICAL METHODS

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cancer is presently one of the most studied lifestyle disease. Its treatment is among others based on chemotherapy. One of the drugs used in chemotherapy is doxorubicin, which interacts with DNA and inhibits division of tumour cells. For better usage of this compound as drug, it is necessary to know its interactions with DNA. In work, interactions between doxorubicin and DNA were monitored using electrochemical methods. In addition, intarcalation of doxorubicin into DNA isolated from resistant as well as sentisive tumour cells was monitored and mutual correlation was searched. Cancer is presently one of the most studied lifestyle disease. Its treatment is among others based on chemotherapy. One of the drugs used in chemotherapy is doxorubicin, which interacts with DNA and inhibits division of tumour cells. For better usage of this compound as drug, it is necessary to know its interactions with DNA. In work, interactions between doxorubicin and DNA were monitored using electrochemical methods. In addition, intarcalation of doxorubicin into DNA isolated from resistant as well as sentisive tumour cells was monitored and mutual correlation was searched. (en)
Title	MONITORING OF DNA-DOXORUBICIN INTERACTIONS BY ELECTROCHEMICAL METHODS MONITORING OF DNA-DOXORUBICIN INTERACTIONS BY ELECTROCHEMICAL METHODS (en)
skos:prefLabel	MONITORING OF DNA-DOXORUBICIN INTERACTIONS BY ELECTROCHEMICAL METHODS MONITORING OF DNA-DOXORUBICIN INTERACTIONS BY ELECTROCHEMICAL METHODS (en)
skos:notation	RIV/00216305:26220/10:PU89913!RIV14-MSM-26220___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED2.1.00/03.0072), P(GA102/08/1546), P(GAP301/10/0356), P(IAA401990701), P(KAN208130801)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Húska, Dalibor Hubálek, Jaromír
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Fakulta elektrotechniky a komunikačních technologií
http://linked.open...dnocenehoVysledku	272476
http://linked.open...ai/riv/idVysledku	RIV/00216305:26220/10:PU89913
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	doxorubicin, DNA, tumour cells (en)
http://linked.open.../riv/klicoveSlovo	tumour cells DNA doxorubicin
http://linked.open...ontrolniKodProRIV	[9A3D5D4D96EC]
http://linked.open...v/mistoKonaniAkce	Brno
http://linked.open...i/riv/mistoVydani	Brno
http://linked.open...i/riv/nazevZdroje	X. Pracovní setkání fyzikálních chemiků a elektrochemiků
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre of sensor, information and communication systems Study of contribution of different DNA-damaging mechanisms to toxicity of cytostatics to human chemosensitive and chemoresistant neuroblastomas Study of binding of platinum cytostatics to DNA structure; Influence of metallothionein New design and exploiting nanobiosensors and nanosensors to target medicine (NANOSEMED) Miniaturized intelligent systems and nanostructured elektrodes for chemical, biological, and pharmaceutical applications (NANIMEL)
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Babula, Petr Eckschlager, Tomáš Hubálek, Jaromír Húska, Dalibor Kizek, René Stiborová, Marie Kynclová, Hana
http://linked.open...vavai/riv/typAkce	CST - Celostátní
http://linked.open.../riv/zahajeniAkce	2010-06-23 (xsd:date)
number of pages	3 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Mendelová univerzita v Brně
https://schema.org/isbn	978-80-7375-396-2
http://localhost/t...ganizacniJednotka	26220

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