About: Epigenetic Regulation of Telomere Maintenance

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.karger.com/Article/Pdf/360775
Description	As chromatin structures, telomeres undergo epigenetic regulation of their maintenance and function. In plants, these processes are likely of a higher complexity than in animals or yeasts, as exemplified by methylation of cytosines in plant telomeric DNA or reversible developmental regulation of plant telomerase. We highlight the dual role of telomeres from the epigenetic point of view: (i) as chromatin structures that are the subject of epigenetic regulation (e. g. DNA and histone modifications), and (ii) as chromosome domains acting themselves as epigenetic regulatory elements (e. g. in the telomere position effect). Possibly, some molecular tools (e. g. telomeric transcripts) are common to both these aspects of telomere epigenetics. We further discuss the justification for the classical textbook view of telomeres as heterochromatic structures. (C) 2014 S. Karger AG, Basel As chromatin structures, telomeres undergo epigenetic regulation of their maintenance and function. In plants, these processes are likely of a higher complexity than in animals or yeasts, as exemplified by methylation of cytosines in plant telomeric DNA or reversible developmental regulation of plant telomerase. We highlight the dual role of telomeres from the epigenetic point of view: (i) as chromatin structures that are the subject of epigenetic regulation (e. g. DNA and histone modifications), and (ii) as chromosome domains acting themselves as epigenetic regulatory elements (e. g. in the telomere position effect). Possibly, some molecular tools (e. g. telomeric transcripts) are common to both these aspects of telomere epigenetics. We further discuss the justification for the classical textbook view of telomeres as heterochromatic structures. (C) 2014 S. Karger AG, Basel (en)
Title	Epigenetic Regulation of Telomere Maintenance Epigenetic Regulation of Telomere Maintenance (en)
skos:prefLabel	Epigenetic Regulation of Telomere Maintenance Epigenetic Regulation of Telomere Maintenance (en)
skos:notation	RIV/00216224:14740/14:00074401!RIV15-MSM-14740___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(ED1.1.00/02.0068), P(EE2.3.20.0043), P(EE2.3.20.0189), P(GAP501/11/0289), P(GAP501/11/0596)
http://linked.open...iv/cisloPeriodika	1-3
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Fojtová, Miloslava Fajkus, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	14854
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/14:00074401
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Chromatin; DNA methylation; Epigenetics; Histone modifications; Telomerase; Telomere; Telomeric transcripts (en)
http://linked.open.../riv/klicoveSlovo	Histone modifications Telomeric transcripts Epigenetics Telomerase DNA methylation Telomere Chromatin
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[ACF12DCFDA70]
http://linked.open...i/riv/nazevZdroje	Cytogenetic and Genome research
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Development of excellence in evolutionary cytogenomics, epigenetics and cell signalling Human Resources Development for R&D and Innovation in the Field of Genomics and Proteomics of Plant Systems Central european institute of technology Loss of specific DNA repeats in response to dysfunction of CAF1 in plants Epigenetic mechanisms of plant telomeres regulation
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	143
http://linked.open...iv/tvurceVysledku	Fajkus, Jiří Fojtová, Miloslava
http://linked.open...ain/vavai/riv/wos	000342614100013
issn	1424-8581
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1159/000360775
http://localhost/t...ganizacniJednotka	14740

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