About: Disturbed Default Mode Network Connectivity Patterns in Alzheimer's Disease Associated with Visual Processing

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About: Disturbed Default Mode Network Connectivity Patterns in Alzheimer's Disease Associated with Visual Processing Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	https://iospress.metapress.com/content/y7477621420j4145/resource-secured/?target=fulltext.pdf
Description	Changes in connectivity of the posterior node of the default mode network (DMN) were studied when switching from baseline to a cognitive task using functional magnetic resonance imaging. In all, 15 patients with mild to moderate Alzheimer's disease (AD) and 18 age-, gender-, and education-matched healthy controls (HC) participated in the study. Psychophysiological interactions analysis was used to assess the specific alterations in the DMN connectivity (deactivation-based) due to psychological effects from the complex visual scene encoding task. In HC, we observed task-induced connectivity decreases between the posterior cingulate and middle temporal and occipital visual cortices. These findings imply successful involvement of the ventral visual pathway during the visual processing in our HC cohort. In AD, involvement of the areas engaged in the ventral visual pathway was observed only in a small volume of the right middle temporal gyrus. Changes in connectivity of the posterior node of the default mode network (DMN) were studied when switching from baseline to a cognitive task using functional magnetic resonance imaging. In all, 15 patients with mild to moderate Alzheimer's disease (AD) and 18 age-, gender-, and education-matched healthy controls (HC) participated in the study. Psychophysiological interactions analysis was used to assess the specific alterations in the DMN connectivity (deactivation-based) due to psychological effects from the complex visual scene encoding task. In HC, we observed task-induced connectivity decreases between the posterior cingulate and middle temporal and occipital visual cortices. These findings imply successful involvement of the ventral visual pathway during the visual processing in our HC cohort. In AD, involvement of the areas engaged in the ventral visual pathway was observed only in a small volume of the right middle temporal gyrus. (en)
Title	Disturbed Default Mode Network Connectivity Patterns in Alzheimer's Disease Associated with Visual Processing Disturbed Default Mode Network Connectivity Patterns in Alzheimer's Disease Associated with Visual Processing (en)
skos:prefLabel	Disturbed Default Mode Network Connectivity Patterns in Alzheimer's Disease Associated with Visual Processing Disturbed Default Mode Network Connectivity Patterns in Alzheimer's Disease Associated with Visual Processing (en)
skos:notation	RIV/00216224:14740/14:00074326!RIV15-MSM-14740___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(GAP103/12/0552)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Rektorová, Irena Mikl, Michal Mareček, Radek Krajčovičová, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	11872
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/14:00074326
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Alzheimer's disease; default mode network; functional MRI; posterior cingulate; visual processing (en)
http://linked.open.../riv/klicoveSlovo	functional MRI posterior cingulate Alzheimer's disease default mode network visual processing
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[33444E206F02]
http://linked.open...i/riv/nazevZdroje	JOURNAL OF ALZHEIMERS DISEASE
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Comparison and inference of methods for evaluation of functional and effective connectivity in fMRI Central european institute of technology
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	41
http://linked.open...iv/tvurceVysledku	Rektorová, Irena Mikl, Michal Mareček, Radek Krajčovičová, Lenka
http://linked.open...ain/vavai/riv/wos	000340488400019
issn	1387-2877
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.3233/JAD-131208
http://localhost/t...ganizacniJednotka	14740

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