About: Electrochemical and Spectral Analysis of Cytosine and Guanine Homo-oligodeoxynucleotides

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About: Electrochemical and Spectral Analysis of Cytosine and Guanine Homo-oligodeoxynucleotides Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Oligodeoxynucleotides (ODNs) with repetitive cytosine (C) or guanine (G) sequences are observed in the promoter region of the oncogenes and of human telomeric DNA. Here we present electrochemical and spectral studies of short C or G homo-ODNs in solutions with different pH. Electrochemistry was represented by linear sweep or cyclic voltammetry in connection with a hanging mercury drop electrode (HMDE). As a spectral method circular dichroism was used. It was found that cytosine ODNs form stable structures, the so-called i-motifs and guanine ODN structures form tetraplex via a G-quartet. Both structures are dependent on pH and the ODN chain length. Oligodeoxynucleotides (ODNs) with repetitive cytosine (C) or guanine (G) sequences are observed in the promoter region of the oncogenes and of human telomeric DNA. Here we present electrochemical and spectral studies of short C or G homo-ODNs in solutions with different pH. Electrochemistry was represented by linear sweep or cyclic voltammetry in connection with a hanging mercury drop electrode (HMDE). As a spectral method circular dichroism was used. It was found that cytosine ODNs form stable structures, the so-called i-motifs and guanine ODN structures form tetraplex via a G-quartet. Both structures are dependent on pH and the ODN chain length. (en) Oligodeoxynucleotides (ODNs) with repetitive cytosine (C) or guanine (G) sequences are observed in the promoter region of the oncogenes and of human telomeric DNA. Here we present electrochemical and spectral studies of short C or G homo-ODNs in solutions with different pH. Electrochemistry was represented by linear sweep or cyclic voltammetry in connection with a hanging mercury drop electrode (HMDE). As a spectral method circular dichroism was used. It was found that cytosine ODNs form stable structures, the so-called i-motifs and guanine ODN structures form tetraplex via a G-quartet. Both structures are dependent on pH and the ODN chain length. (cs)
Title	Electrochemical and Spectral Analysis of Cytosine and Guanine Homo-oligodeoxynucleotides Electrochemical and Spectral Analysis of Cytosine and Guanine Homo-oligodeoxynucleotides (en) Electrochemical and Spectral Analysis of Cytosine and Guanine Homo-oligodeoxynucleotides (cs)
skos:prefLabel	Electrochemical and Spectral Analysis of Cytosine and Guanine Homo-oligodeoxynucleotides Electrochemical and Spectral Analysis of Cytosine and Guanine Homo-oligodeoxynucleotides (en) Electrochemical and Spectral Analysis of Cytosine and Guanine Homo-oligodeoxynucleotides (cs)
skos:notation	RIV/00216224:14310/14:00075817!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(LH13053)
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Trnková, Libuše Gurecký, Libor
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	14090
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/14:00075817
http://linked.open...riv/jazykVysledku	cze - čeština
http://linked.open.../riv/klicovaSlova	Oligodeoxynucleotides (ODNs); Homo-ODN; Cytosin (C); Guanin (G); Cyclic Voltammetry (CV); Linear Sweep Voltammetry (LSV); Elimination Voltammetric procedure (EVP); Circular Dichroism (CD) (en)
http://linked.open.../riv/klicoveSlovo	Circular Dichroism (CD) Cyclic Voltammetry (CV) Cytosin (C) Elimination Voltammetric procedure (EVP) Guanin (G) Homo-ODN Linear Sweep Voltammetry (LSV) Oligodeoxynucleotides (ODNs)
http://linked.open...ontrolniKodProRIV	[E71B6C1DBAB1]
http://linked.open...v/mistoKonaniAkce	Jetřichovice
http://linked.open...i/riv/mistoVydani	Jetřichovice
http://linked.open...i/riv/nazevZdroje	XXXIV. Moderní Elektrochemické Metody
http://linked.open...in/vavai/riv/obor	CF
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Chemical and electrochemical analysis of purine derivatives and their copper complexes Central european institute of technology
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Trnková, Libuše Gurecký, Libor
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2014-01-01 (xsd:date)
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Srsenová Lenka - Best servis Ústí nad Labem
https://schema.org/isbn	9788090522121
http://localhost/t...ganizacniJednotka	14310

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