About: Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease

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About: Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	BACKGROUND AND PURPOSEThe basal ganglia and the cerebellum have both emerged as important structures involved in the processing of temporal information. METHODSWe examined the roles of the cerebellum and striatum in predictive motor timing during a target interception task in healthy individuals (HC group; n = 21) and in patients with early Parkinson's disease (early stage PD group; n = 20) using functional magnetic resonance imaging. RESULTSDespite having similar hit ratios, the PD failed more often than the HC to postpone their actions until the right moment and to adapt their behavior from one trial to the next. We found more activation in the right cerebellar lobule VI in HC than in early stage PD during successful trials. Successful trial-by-trial adjustments were associated with higher activity in the right putamen and lobule VI of the cerebellum in HC. CONCLUSIONSWe conclude that both the cerebellum and striatum are involved in predictive motor timing tasks. BACKGROUND AND PURPOSEThe basal ganglia and the cerebellum have both emerged as important structures involved in the processing of temporal information. METHODSWe examined the roles of the cerebellum and striatum in predictive motor timing during a target interception task in healthy individuals (HC group; n = 21) and in patients with early Parkinson's disease (early stage PD group; n = 20) using functional magnetic resonance imaging. RESULTSDespite having similar hit ratios, the PD failed more often than the HC to postpone their actions until the right moment and to adapt their behavior from one trial to the next. We found more activation in the right cerebellar lobule VI in HC than in early stage PD during successful trials. Successful trial-by-trial adjustments were associated with higher activity in the right putamen and lobule VI of the cerebellum in HC. CONCLUSIONSWe conclude that both the cerebellum and striatum are involved in predictive motor timing tasks. (en)
Title	Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease (en)
skos:prefLabel	Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease (en)
skos:notation	RIV/00216224:14110/14:00076462!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Mikl, Michal Bareš, Martin Mareček, Radek Husárová, Ivica
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	17659
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/14:00076462
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Basal ganglia; cerebellum; fMRI; Parkinson's disease; prediction; timing (en)
http://linked.open.../riv/klicoveSlovo	timing Basal ganglia Parkinson's disease prediction cerebellum fMRI
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[C38E0E93F709]
http://linked.open...i/riv/nazevZdroje	Journal of Neuroimaging
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Bareš, Martin Mikl, Michal Gescheidt, Tomáš Mareček, Radek Krupa, Petr Lungu, Ovidiu V Čechová, Ivica
http://linked.open...ain/vavai/riv/wos	000329509100008
http://linked.open...n/vavai/riv/zamer	The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions
issn	1051-2284
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/j.1552-6569.2011.00663.x
http://localhost/t...ganizacniJednotka	14110

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