About: FCB - Fluorine Conversion Box     Goto   Sponge   NotDistinct   Permalink

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Description
  • The project is focused on design, construction and testing FCB (fluorine conversion box) for production of F-18 in electrophilic form. Two possible approaches are to be used: either plasma creation in a discharge chamber, or reactions driven by UV radiation in an absorption cell. The FCB is considered to be an auxilliary unit for current synthetizing modules in order to reach both high entrance activities of F-18 and its high specific activity (in order of GBq/µmol) in the electrophilic reactions for low cost. The project aims at providing workplaces with a new technology for production of PET radiopharmaceuticals and allow for commercial production of the FCB module. (en)
  • Projekt je zaměřen na návrh, konstrukci a ověřovací provoz FCB modulu - konverzního modulu na tvorbu elektrofilního izotopu fluoru F-18 založeného na dvou přístupech, a to jednak na bázi tvorby v plazmatu ve výbojové cele, jednak na reakcích při absorpci UV záření v absorpční cele. FCB je koncipován jako přídavná jednotka ke stávajícím syntetizačním modulům s cílem dosáhnout vysokých vstupních aktivit fluoru F-18 do elektrofilních reakcí s vysokou měrnou aktivitou v řádu GBq/µmol za nízké pořizovací náklady. Cílem projektu je vybavit pracoviště novou technologií pro účely vývoje PET radiofarmak a umožnit komerční výrobu FCB modulu.
Title
  • FCB - Fluorine Conversion Box (en)
  • FCB - modul pro konverzi radionuklidu F-18 na elektrofilní formu
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  • TA03010315
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  • FCB- FCB module- Fluorine conversion box- Electrophilic module- Electrophilic labeling- Electrophilic cell- Electrophi- lic discharge chamber- Electrophilic absorption cell- electrophilic labeling with F-18 (en)
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