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| Description
| - The object of the project is fibrinogen, a key protein of blood coagulation. Mutations in fibrinogen are found in congenital dysfibrinogenemias. Methods of molecular genetics, proteomics and fibrinogen functional testing will be used. (en)
- Předmětem studia je fibrinogen, který hraje klíčovou úlohu v procesu hemostázy. U vrozených dysfibrinogenemií nalézáme mutace ve struktuře fibrinogenu. Bude použito metod molekulární genetiky, proteomiky a vyšetření funkčních vlastností fibrinogenu.
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| Title
| - Congenital and acquired dysfibrinogenemias and hypofibrinogenemias (en)
- Vrozené a získané dysfibrinogenemie a hypofibrinogenemie
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| skos:notation
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| http://linked.open...avai/cep/aktivita
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| http://linked.open...kovaStatniPodpora
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| http://linked.open...ep/celkoveNaklady
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| http://linked.open...datumDodatniDoRIV
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| http://linked.open...i/cep/druhSouteze
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| http://linked.open...ep/duvernostUdaju
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| http://linked.open.../cep/fazeProjektu
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| http://linked.open...ai/cep/hlavniObor
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| http://linked.open...hodnoceniProjektu
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| http://linked.open...vai/cep/kategorie
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| http://linked.open.../cep/klicovaSlova
| - fibrinogen; fibrin; dysfibrinogenemia; hypofibrinogenemia; coagulation; fibrinolysis; mutation; genetical analysis (en)
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| http://linked.open...ep/partnetrHlavni
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| http://linked.open...inujicichPrijemcu
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| http://linked.open...cep/pocetPrijemcu
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| http://linked.open...ocetSpoluPrijemcu
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| http://linked.open.../pocetVysledkuRIV
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| http://linked.open...enychVysledkuVRIV
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| http://linked.open...lneniVMinulemRoce
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| http://linked.open.../prideleniPodpory
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| http://linked.open...iciPoslednihoRoku
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| http://linked.open...atUdajeProjZameru
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| http://linked.open.../vavai/cep/soutez
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| http://linked.open...usZobrazovaneFaze
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| http://linked.open...ai/cep/typPojektu
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| http://linked.open...ep/ukonceniReseni
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| http://linked.open...ep/zahajeniReseni
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| http://linked.open...jektu+dodavatelem
| - 22 bear a mutation for dysfibrinogenemia - 20 in the Aalpha, 1 in the Bbeta, and 1 in the gama chain; 3 with thromboses (B beta R237A, gama Y363N, A alfa N106D); 5 cases with mutation D320H, Bbeta N351K, Aalfa F98Y, gama T211. (en)
- U 22 pacientů mutace dysfibrinogenemie - 20 v Aalfa řetězci, 1 v Bbeta řetězci, 1 v gama řetězci; u 3 s trombózami (B beta R237A, gama Y363N, A alfa N106D). U 4 mutace Bbeta D320H, Bbeta N351K, Aalfa F98Y, gama T211. (cs)
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| http://linked.open...tniCyklusProjektu
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| http://linked.open.../cep/klicoveSlovo
| - fibrinogen
- coagulation
- mutation
- dysfibrinogenemia
- fibrin
- fibrinolysis
- hypofibrinogenemia
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| is http://linked.open...vavai/cep/projekt
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