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| Description
| - Determine correlation among intrarenal expression of MCP-1, RANTES, TGF-beta1, HGF and BMP genes, infiltration of leukocyte into renal tissue, proteinuria and short term otcome of IgA nephropathy. Find out if patients with genotype related to high inflammatory cytokines production are in higher risk for higher proteinuria and progression of IgA nephropathy. (en)
- Sledovat korelaci mezi intrarenální expresí genů pro MCP-1, RANTES, TGFbeta1, HGF a BMP, infiltací ledvinné tkáně leukocyty, výší proteinurie a progrese IgA nefropatie Zjistit, zda nositelé vlohy pro vysokou produkci prozánětlivých cytokinů mají vyšší riziko vzniku klinicky závažné proteinurie a progrese IgA nefropatie
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| Title
| - The expression of proinflammatory genes in patients with IgA nephropathy and their relation to the disease outcome (en)
- Exprese prozánětlivých genů u nemocných s IgA nefropatií a jejich vztah k průběhu onemocnění
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| skos:notation
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| http://linked.open...avai/cep/aktivita
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| http://linked.open...kovaStatniPodpora
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| http://linked.open...ep/celkoveNaklady
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| http://linked.open...datumDodatniDoRIV
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| http://linked.open...i/cep/druhSouteze
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| http://linked.open...ep/duvernostUdaju
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| http://linked.open.../cep/fazeProjektu
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| http://linked.open...ai/cep/hlavniObor
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| http://linked.open...hodnoceniProjektu
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| http://linked.open...vai/cep/kategorie
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| http://linked.open.../cep/klicovaSlova
| - IgA nephropathy; biopsy; gene expression; proteinuria; fibrosis; polymorphism; cytokines (en)
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| http://linked.open...ep/partnetrHlavni
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| http://linked.open...inujicichPrijemcu
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| http://linked.open...cep/pocetPrijemcu
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| http://linked.open...ocetSpoluPrijemcu
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| http://linked.open.../pocetVysledkuRIV
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| http://linked.open...enychVysledkuVRIV
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| http://linked.open...lneniVMinulemRoce
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| http://linked.open.../prideleniPodpory
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| http://linked.open...iciPoslednihoRoku
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| http://linked.open...atUdajeProjZameru
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| http://linked.open.../vavai/cep/soutez
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| http://linked.open...usZobrazovaneFaze
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| http://linked.open...ai/cep/typPojektu
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| http://linked.open...ep/ukonceniReseni
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| http://linked.open...ep/zahajeniReseni
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| http://linked.open...jektu+dodavatelem
| - Analýza genové exprese vybraných molekulárních markerů ve tkáni ledvin doložila vyšší prediktivní význam při progresi nefropatií, než dosud používané markery resp. rizikové faktory. (cs)
- Analysis of gene expression of selected molecular markers in kidney tissue revealed higher predictive significance in progression of studied nephropathies, compared to standard markers and risk factors of progression. (en)
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| http://linked.open...tniCyklusProjektu
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| http://linked.open.../cep/klicoveSlovo
| - IgA nephropathy
- gene expression
- polymorphism
- biopsy
- fibrosis
- proteinuria
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| is http://linked.open...vavai/cep/projekt
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