About: Dipeptidyl peptidase IV activity and/or structure homologues (DASH) in the brain tumors. Emerging factors in cancer pathogenesis?     Goto   Sponge   NotDistinct   Permalink

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Description
  • Expression and enzyme activity of %22Dipeptidyl peptidase-IV activity and/or structure homologues%22 (DASH) in human gliomas. Biochemical, histochemical, immunochemical and molecular biology techniques will be used. Project shold confirm hypotheized role of the new group of molecules in human glioma pathogenesis, to assess possible exploitation of DASH molecules for refining of histopathological diagnostics and their value as a disease prognosis indicators. (en)
  • Biochemickými, histochemickými, imunochemickými a molekulárně biologickými přístupy bude studována exprese a enzymová aktivita %22Dipeptidylpeptidase IV strukturou a/nebo aktivitou homologních%22 (DASH) molekul v tkáních gliálních tumorů. Studie má ověřit hypotesu o významu nové skupiny molekul ve vzniku a rozvoji lidských gliomů a posoudit využitelnost DASH molekul pro upřesnění histopatologické diagnostiky a odhad prognosy tohoto onemocnění.
Title
  • Dipeptidyl peptidase IV activity and/or structure homologues (DASH) in the brain tumors. Emerging factors in cancer pathogenesis? (en)
  • Dipeptidyl peptidase IV aktivitou a/nebo strukturou homologní molekuly v tumorech centrálního nervového systému. Nová skupina molekul v nádorové patogenesi?
skos:notation
  • NR8105
http://linked.open...avai/cep/aktivita
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  • Cancer; CNS; Pathogenesis; Dipeptidylpeptidase; Attractin; Protease; Regulation; Prognosis (en)
http://linked.open...ep/partnetrHlavni
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http://linked.open...cep/pocetPrijemcu
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  • Objevení nového prediktivního faktoru u gliálních nádorů CNS-DPP-IV podobná enzymatická aktivita. Tato aktivita positivně koreluje s gradem a je vyšší u nádorů, které recidivovaly. (cs)
  • Detection of new predictive factor in glial tumors of central nervous system - DPP-IV like enzymatic activity. This activity positively correlate with tumor grade and is increased in recurrent tumors. (en)
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • Cancer
  • CNS
  • Regulation
  • Attractin
  • Dipeptidylpeptidase
  • Pathogenesis
  • Protease
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