About: Metabolism of steroids in inflamatory bowel disease     Goto   Sponge   NotDistinct   Permalink

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Description
  • Are there changes of activity and gene expresion of dehydrogenases 11 beta hydrosteroids 1 and 2 (11 HSD 1 and 11 HSD 2) in patients suffering from inflammatory bowel disease (Crohn´s disease and ulcerative colitis ?). Are there changes of isoforms 11 HSD in patients with inflammatory bowel disease similar to changes in experimental animal models of Crohn´s disease and ulcerative colitis ? (en)
  • Dochází u pacientů se zánětlivými chorobami střevními ke změnám v aktivitě a genové exprese enzymu dehydrogenázy 11 beta hydropoxysteroidů 1 (11HSD1) a dehydrogenázy 11 beta hydroxysteroidů 2 (11 HSD 2) ? Jsou změny isiforem 11 HSD u pacientů s Crohnovou chorobou a ulcerozní kolitidou stejné jako u experimentálních modelů těchto chorob u potkana ?
Title
  • Metabolism of steroids in inflamatory bowel disease (en)
  • Metabolizmus steroidů u zánětlivých chorob střevních
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  • NK6723
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  • inflammatory bowel disease;hydroxysteroid dehydrodenases;Crohn´s disease;glucocorticoid;experimental models;animal;human;biopsy (en)
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  • Nové pohledy na příčiny kortikorezistence a kortikodependence u pacientů s Crohnovou chorobou a ulcerozní kolitidou. (cs)
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  • animal
  • human
  • Crohn´s disease
  • glucocorticoid
  • inflammatory bowel disease
  • experimental models
  • hydroxysteroid dehydrodenases
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