About: Influencing of an oxidative stress, risk of impaired glucose tolerance, type 2 diabetes mellitus and preclinical atherosclerosis by treatment of hyperlipidemias.     Goto   Sponge   NotDistinct   Permalink

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  • Possibilities of favourable influencing of mechanisms leading to impaired glucose tolerance and DM 2 development will be observed in yet untreated patients with primary hypercholesterolemia and/or hypertriglyceridemia by using the statins or fibrates. Concomitantly the markers of preclinical atherosclerosis will be followed during the long-term hypolipidemic therapy. (en)
  • U dosud neléčených pacientů s primární hypercholesterolémií a hypertriglyceridémií budou sledovány možnosti příznivého ovlivnění mechanismů, vedoucích k poruše glukózové tolerance a rozvoje diabetu mellitu 2.typu léčbou statiny a fibráty. Současně budou v průběhu dlouhodobé hypolipidemické léčby budou sledovány markery preklinické aterosklerozy.
Title
  • Influencing of an oxidative stress, risk of impaired glucose tolerance, type 2 diabetes mellitus and preclinical atherosclerosis by treatment of hyperlipidemias. (en)
  • Ovlivnění oxidačního stresu, rizika vzniku porušené glukozové tolerance, diabetu mellitu 2. typu a preklinické aterosklerózy léčbou hyperlipidémie.
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  • NB7377
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  • Hypercholesterolemia;hypertriglyceridemia;lipoperoxidation;indices of inflammation;endothelial dysfunction;impaired glucose tolerance;type 2 diabetes mellitus (en)
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  • Roční hypolipidemická léčba vedla u nemoc.s primárními hyperlipoproteinémiemi k příznivému ovlivnění ukazatelů oxidačního stresu a některých parametrů zánětu a endoteliální dysfunkce,úpravu inzulínové rezist. ani glukózové tolerance jsme neprokázali. (cs)
  • Year lasting hypolipidemic treatment led in the patients with primary hyperlipoproteinemias to favorable improvement of the paramaters of oxidative stress,endothelial dysfunct. and of some inflammation indices,nor insulin resist.or glucose tolerance. (en)
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  • endothelial dysfunction
  • hypertriglyceridemia
  • Hypercholesterolemia
  • lipoperoxidation
  • impaired glucose tolerance
  • indices of inflammation
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