About: Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus     Goto   Sponge   NotDistinct   Permalink

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Description
  • Identification of principles of collaborative action of actin-related (Arp6) and mypson (NM1) proteins in functional organization of the cell nucleus and chromatin. The project aims to asses especially their contribution to the organization of chromosomes, to the dynamics of chromatin movements, and to the formation of tranion-competent chromatin. (en)
  • Zjištění principů spolupráce proteinů Arp6 a NM1 ve funkční organizaci buněčného jádra a chromatinu, především pak jejich příspěvek k organizaci chromozomů v jádře, dynamice pohybu chromatinu a tvorbě chromatinu schopného přepisu genetické informace.
Title
  • Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus (en)
  • Příspěvek proteinových rodin aktinu a myosinu k dynamice a transkripci chromatinu v buněčném jádře.
skos:notation
  • ME09101
http://linked.open...avai/cep/aktivita
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  • cell nucleus; myosin I; Arp proteins; actin; chromatin; chromosom; tranion; regulation of gene expression (en)
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  • The project described interactions between Arp proteins and the nuclear myosin I (NM1,) and their functions in organization of the nuclear interior. Special cell lines deficient for Arps/NM1 were developed. New data were acquired (2 published articles, 1 manuscript, 1 manuin preparation, 3 conference presentations) the project also improved intensified studies of our PhD students (en)
  • Projekt se zabýval popisem spolupráce proteinů typu Arp a jaderným myosinem (NM1) a jejich funkcemi v organizaci buněčného jádra. K tomuto účelu byly vyvinuty speciální buněčné linie deficientní pro NM1 a Arp proteiny. V projektu byly získány nové vědecké poznatky (2 články vyšlé, 1 manuskript, 1 manuskript v přípravě, 3 prezentace na konferencích) a projekt zkvalitnil výchovu PhD studentů. (cs)
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • cell nucleus
  • actin
  • chromatin
  • Arp proteins
  • chromosom
  • myosin I
  • tranion
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