About: Membrane signalosomes of mast cells and basophils - targets for innovative therapies     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description
  • The aim of this project is: 1. To contribute to determining the composition of the FceRI membrane signalosomes important for antigen-induced degranulation in mast cells. 2. To contribute to determining the composition of membrane signalosomes important for antigen-induced adhesion and chemotaxis in mast cells. 3. To determine new modulators (inhibitors/activators) of antigen-induced degranulation, adhesion and chemotaxis in mouse and human mast cells. (en)
  • Cílem projektu je 1. Přispět k určení složení FceRI membránových signalosomů důležitých pro degranulaci žírných buněk. 2. Přispět k určení složení membránových signalosomů důležitých pro antigenem indukovanou adhezi a chemotaxi u žírných buněk 3. Určit nové modulátory (inhibitory/aktivátory) antigenem indukované adheze, chemotaxe a degranulace u myších a lidských žírných buněk.
Title
  • Membrane signalosomes of mast cells and basophils - targets for innovative therapies (en)
  • Membránové signalosomy žírných buněk a bazofilů - cíle pro inovativní terapie
skos:notation
  • LD12073
http://linked.open...avai/cep/aktivita
http://linked.open...kovaStatniPodpora
http://linked.open...ep/celkoveNaklady
http://linked.open...datumDodatniDoRIV
http://linked.open...i/cep/druhSouteze
http://linked.open...ep/duvernostUdaju
http://linked.open.../cep/fazeProjektu
http://linked.open...ai/cep/hlavniObor
http://linked.open...vai/cep/kategorie
http://linked.open.../cep/klicovaSlova
  • mast cell; IgE receptor; immunoreceptor-induced activation; shRNA; lentiviral transduction (en)
http://linked.open...ep/partnetrHlavni
http://linked.open...inujicichPrijemcu
http://linked.open...cep/pocetPrijemcu
http://linked.open...ocetSpoluPrijemcu
http://linked.open.../pocetVysledkuRIV
http://linked.open...enychVysledkuVRIV
http://linked.open...lneniVMinulemRoce
http://linked.open.../prideleniPodpory
http://linked.open...iciPoslednihoRoku
http://linked.open...atUdajeProjZameru
http://linked.open.../vavai/cep/soutez
http://linked.open...usZobrazovaneFaze
http://linked.open...ai/cep/typPojektu
http://linked.open...ep/ukonceniReseni
http://linked.open.../cep/vedlejsiObor
http://linked.open...ep/zahajeniReseni
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • mast cell
  • IgE receptor
  • immunoreceptor-induced activation
  • shRNA
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