About: Metal oxide nanoparticle modified monolithic supports for bioanalysis     Goto   Sponge   NotDistinct   Permalink

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Description
  • The aim of this project is the development of organic polymer monolithic supports modified with metal oxide nanoparticles and their integration into multidimensional miniaturized systems for analysis of proteins and peptides. Nickel oxide and iron oxide nanoparticles will be synthesized using various wet chemical methods such as co-precipitation and thermal decomposition. The methacrylate based monolithic supports will be prepared by thermally and UV initiated polymerization in fused silica capillaries and the metal oxide nanoparticles will be immobilized on their pore surfaces using various chemistries. The effect of particle size as well as morphology and chemistry of monolithic support on the nanoparticle immobilization and chromatographic performance of developed columns will be studied in detail. These new types of monolithic capillary columns will be applied for separation of proteins and selective enrichment of phoshopeptides. (en)
  • Syntéza, modifikace a imobilizace nanočástic oxidů kovů na organické polymerní monolity s cílem vyvinout nové typy sorbentů pro analýzu peptidů a proteinů.
Title
  • Metal oxide nanoparticle modified monolithic supports for bioanalysis (en)
  • Monolity modifikované nanočásticemi oxidů kovů pro bioanalýzu
skos:notation
  • GPP206/11/P004
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  • nanočástice oxidů kovů; monolit; syntéza; bioanalýza (en)
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  • monolit
  • syntéza
  • nanočástice oxidů kovů
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