About: The influence of the eicosanoid biosynthesis inhibitors to immunity of the wax moth Galleria mellonella     Goto   Sponge   NotDistinct   Permalink

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Description
  • The innate immune system of insects includes cellular and humoral reactions. In regulation of these reactions, eicosanoids - metabolites of arachidonic acid, play an important role. Their production can be modulated using eicosanoid biosynthesis inhibitors (EBI). The main aim of this project is to study insect immune system (reactive oxygen and nitrogen metabolites production, hemolymph antibacterial activity, phenoloxidase activity, lysozyme content, hemolymph protein profiles and interactions with Photorhabdus bacteria) using the wax moth Galleria mellonella as a model and modulation of the immune system parameters under inhibition of different pathways of eicosanoid biosynthesis (using different EBIs). The specific role of the particular pathway(s) will be investigated, and effective antibacterial inhibitors/stimulators will be selected with regard to their possible use in agriculture and breeding. (en)
  • Cílem je studium imunitního systému hmyzu (produkce RKM a RDM hemocyty, antibakteriální aktivita hemolymfy, aktivita phenoloxidázy, množství lysozymu a proteinové změny v hemolymfě, interakce s entomopatogenními bakteriemi rodu Photorhabdus) po působení inhibitorů různých drah biosyntézy eikosanoidů
Title
  • The influence of the eicosanoid biosynthesis inhibitors to immunity of the wax moth Galleria mellonella (en)
  • Vliv inhibitorů biosyntézy eikosanoidů na imunitu zavíječe voskového Galleria mellonella
skos:notation
  • GP206/09/P470
http://linked.open...avai/cep/aktivita
http://linked.open...kovaStatniPodpora
http://linked.open...ep/celkoveNaklady
http://linked.open...datumDodatniDoRIV
http://linked.open...i/cep/druhSouteze
http://linked.open...ep/duvernostUdaju
http://linked.open.../cep/fazeProjektu
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http://linked.open...hodnoceniProjektu
http://linked.open...vai/cep/kategorie
http://linked.open.../cep/klicovaSlova
  • Galleria mellonella; imunita; eikosanoidy; inhibitor (en)
http://linked.open...ep/partnetrHlavni
http://linked.open...inujicichPrijemcu
http://linked.open...cep/pocetPrijemcu
http://linked.open...ocetSpoluPrijemcu
http://linked.open.../pocetVysledkuRIV
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http://linked.open.../prideleniPodpory
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http://linked.open...atUdajeProjZameru
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http://linked.open.../cep/vedlejsiObor
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http://linked.open...jektu+dodavatelem
  • The project gone according to plan both in terms of expertise and in terms of disbursement of funds. (en)
  • Řešení projektu proběhlo podle plánu jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs)
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • Galleria mellonella
  • eikosanoidy
  • imunita
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