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Description
  • Plants and animals evolved significantly different strategies of regulation of the cell proliferation and differentiation. Identification and comparison of molecular mechanisms driving those different strategies in plants, animals and microorganisms might contribute to the identification of their common principles. The project is based on collaboration of laboratories involved in the study of the processes of the cell proliferation and differentiation in those different model organisms including human beings. Collaboration of the laboratories with expertise in (i) molecular plant physiology, (ii) molecular mechanisms maintaining the genome stability, (iii) proliferation, differentiation and programmed cell death of cancer cells and (iv) bioinformatics will result into a multidisciplinary, while still functional team that will guarantee successful solution of scheduled tasks. Participation of multiple, recently collaborating laboratories including Core lab will allow effective employment of high-throughput instrumentation in the planned genomics and proteomics approaches. (en)
  • Cílem projektu je koordinace vědecké činnosti studentů DSP zaměřené na procesy buněčné proliferace a diferenciace u mikrobiálních, rostlinných a živočišných systémů včetně člověka, jejich porovnání a vytvoření modelu obsahujícího specifické, ale i společné rysy jejich molekulární podstaty.
Title
  • Molecular mechanisms of the cell proliferation and differentiation (en)
  • Molekulární mechanismy proliferace a diferenciace buněk
skos:notation
  • GD204/08/H054
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  • regulace proliferace a diferenciace buněk; genomika a proteomika; rostlinné; živočišné a mikrobilární (en)
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  • The project gone according to plan both in terms of expertise and in terms of disbursement of funds. (en)
  • Řešení projektu proběhlo podle plánu jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs)
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  • genomika a proteomika
  • rostlinné
  • regulace proliferace a diferenciace buněk
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