About: Intracellular and extracellular targets for antitumor activity and toxicity of ruthenium complexex     Goto   Sponge   NotDistinct   Permalink

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Description
  • complexex of rhutenium as a new class of promising cytostatics effective in tumor cell resistant to platinum cytostatics (en)
  • komplexy ruthenia jako nová třída slibných cytostatik účinných i v nádorových buňkách resistentních vůči cytostatikům platinovým
Title
  • Intracellular and extracellular targets for antitumor activity and toxicity of ruthenium complexex (en)
  • Vnitrobuněčná a mimobuněčná cílová místa protinádorové aktivity a toxicity komplexů ruthenia
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  • 1P05OC070
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  • intracellular and extracellular targets; antitumor activity; toxicity of ruthenium complexex; cytostatics (en)
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  • Interactions of selected antitumor reuthenium complexes with DNA have been described. The results allowed improving structure-prarmacological relationships of ruthenium complexes. (en)
  • Byly popsány interakce vybraných protinádorově účinných komplexů ruthenia s DNA. Výsledky umožnily zpřesnění vztahů mezi strukturou a farmakologickou aktivitou komplexů ruthenia. (cs)
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  • antitumor activity
  • toxicity of ruthenium complexex
  • intracellular and extracellular targets
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