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rdf:type
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Description
| - A detailed biochemical and molecular biophysics study of the molecular mechanism of action of a new dinuclear PtII complex [{PtCl(1,2-diaminocyclohexane)}2-my-Y]4+, resistant to decomposition by sulfur nucleophiles, was reported herein. The results show that this complex exhibits promising antitumor features as its DNA adducts can largely escape repair and inhibit very effectively transcription.
- A detailed biochemical and molecular biophysics study of the molecular mechanism of action of a new dinuclear PtII complex [{PtCl(1,2-diaminocyclohexane)}2-my-Y]4+, resistant to decomposition by sulfur nucleophiles, was reported herein. The results show that this complex exhibits promising antitumor features as its DNA adducts can largely escape repair and inhibit very effectively transcription. (en)
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Title
| - Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles
- Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles (en)
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skos:prefLabel
| - Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles
- Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles (en)
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skos:notation
| - RIV/68081707:_____/10:00373396!RIV12-AV0-68081707
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1QS500040581), P(GD301/09/H004), P(KAN200200651), P(LC06030), P(ME08017), P(OC08003), P(OC09018), Z(AV0Z50040507), Z(AV0Z50040702), Z(MSM6198959216)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68081707:_____/10:00373396
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - antitumor; dinuclear platinum complex; DNA damage (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Brabec, Viktor
- Zerzánková, Lenka
- Farrell, N. P.
- Suchánková, T.
- Vrána, Oldřich
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.bcp.2009.08.009
|