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Description
| - We investigated the nuclear arrangement of HP1alpha, HP1gamma and TIF1beta proteins during differentiation of embryonic carcinoma P19 cells into primitive endoderm and into the neural pathway. Additionally, the differentiation potential of trichostatin A (TSA) and 5-deoxyazacytidine (5-dAzaC) was studied. Our findings showed that the nuclear arrangement of HP1 subtypes and is differentiation-specific, and seems to be more important than changes in the levels of these proteins, which were relatively stable during all the induced differentiation processes.
- We investigated the nuclear arrangement of HP1alpha, HP1gamma and TIF1beta proteins during differentiation of embryonic carcinoma P19 cells into primitive endoderm and into the neural pathway. Additionally, the differentiation potential of trichostatin A (TSA) and 5-deoxyazacytidine (5-dAzaC) was studied. Our findings showed that the nuclear arrangement of HP1 subtypes and is differentiation-specific, and seems to be more important than changes in the levels of these proteins, which were relatively stable during all the induced differentiation processes. (en)
- V experimentech jsme zkoumali jaderné uspořádání HP1alfa, HP1beta, HP1gama and TIF1beta proteinů během diferenciace embryonálních nádorových buněk P19 do primitivního endodermu a neurálním směrem. Diferenciační potenciál trichostatinu A (TSA) a 5-deoxyazacytidinu (5-dAzaC) byl dále studován. Zjistili jsme, že jaderné uspořádání HP1 subtypů a faktoru TIF1beta je diferenciačně specifické a zdá se být důležitější než množství syntetizovaných proteinů, které bylo relativně stejné během všech indukovaných diferenciačních procesů. (cs)
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Title
| - Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites
- Diferenciačně-specifická asociace HP1alfa a HP1beta s chromocentra koreluje s klastrováním TIF1beta v těchto místech (cs)
- Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites (en)
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skos:prefLabel
| - Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites
- Diferenciačně-specifická asociace HP1alfa a HP1beta s chromocentra koreluje s klastrováním TIF1beta v těchto místech (cs)
- Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites (en)
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skos:notation
| - RIV/68081707:_____/07:00082872!RIV07-AV0-68081707
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1QS500040508), P(GA204/06/0978), P(GP524/03/P171), P(IAA5004306), P(LC535), Z(AV0Z50040507)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68081707:_____/07:00082872
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - HP1 proteiny; TIF1beta; chromocentry (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Histochemistry and Cell Biology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bártová, Eva
- Kozubík, Alois
- Kozubek, Stanislav
- Pacherník, J.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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