| Attributes | Values |
|---|
| rdf:type
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| Description
| - Za podmínek hypoxické inkubace dochází v srdci křepelčího zárodku ke zmnožení kapilár a perzistence trabekul. Abnormální přestavba této primitivní cirkulace vede k anomáliím tepenných kmenů, která vede k fenotypu tenkého kompaktního myokardu a odúmrti. (cs)
- Oxygen availability is one of the necessary prerequisites for normal embryonic development. In our previous study we found that quail embryos incubated under hypoxic conditions (16% O(2)) die at embryonic day (ED) 9 with signs of heart failure. By ED4 and ED6 we found thinner ventricular wall and increased capillary density. We thus hypothesized that the cause of death would lie in severe myocardial and coronary maldevelopment. ED6 and 7 hypoxic hearts had thinner ventricular wall, especially left. There was a simultaneous increase in capillary density, most pronounced in the interventricular septum. This site corresponds to an area of tissue hypoxia and ensuing increased angiogenesis, and also formation of ventricular conduction system. Hypoxia had a positive effect on normal sequence of maturation of the conduction system evaluated by optical mapping at ED7. In sections from ED9 hypoxic hearts we found, in addition to thinner ventricular walls, irregularities in development of coronary tree (miss...
- Oxygen availability is one of the necessary prerequisites for normal embryonic development. In our previous study we found that quail embryos incubated under hypoxic conditions (16% O(2)) die at embryonic day (ED) 9 with signs of heart failure. By ED4 and ED6 we found thinner ventricular wall and increased capillary density. We thus hypothesized that the cause of death would lie in severe myocardial and coronary maldevelopment. ED6 and 7 hypoxic hearts had thinner ventricular wall, especially left. There was a simultaneous increase in capillary density, most pronounced in the interventricular septum. This site corresponds to an area of tissue hypoxia and ensuing increased angiogenesis, and also formation of ventricular conduction system. Hypoxia had a positive effect on normal sequence of maturation of the conduction system evaluated by optical mapping at ED7. In sections from ED9 hypoxic hearts we found, in addition to thinner ventricular walls, irregularities in development of coronary tree (miss... (en)
|
| Title
| - Abnormal myocardial and coronary vasculature development in experimental hypoxia
- Abnormal myocardial and coronary vasculature development in experimental hypoxia (en)
- Abnormální vývoj myokardiální architektury a koronárních cév za podmínek experimentální hypoxie (cs)
|
| skos:prefLabel
| - Abnormal myocardial and coronary vasculature development in experimental hypoxia
- Abnormal myocardial and coronary vasculature development in experimental hypoxia (en)
- Abnormální vývoj myokardiální architektury a koronárních cév za podmínek experimentální hypoxie (cs)
|
| skos:notation
| - RIV/67985904:_____/08:00316951!RIV09-AV0-67985904
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(LC06061), Z(AV0Z50450515), Z(MSM0021620806)
|
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/67985904:_____/08:00316951
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - quail embryo; vasculogenesis; coronary artery (en)
|
| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
|
| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Sedmera, David
- Křížová, P.
- Grim, M.
- Naňka, O.
- Blaha, Milan
- Fikrle, M.
- Tůma, M.
|
| http://linked.open...ain/vavai/riv/wos
| |
| http://linked.open...n/vavai/riv/zamer
| |
| issn
| |
| number of pages
| |
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