About: Voltammetric determination of anticancer drug flutamide at screen-printed carbon electrodes

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About: Voltammetric determination of anticancer drug flutamide at screen-printed carbon electrodes Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Flutamide, 4-nitro-3-trifluoromethyl-isobutylanilide, is the active component of a synthetic nonsteroidal antiandrogen drug, which is commonly used in the treatment of advanced prostate cancer. In this contribution, optimum conditions have been found vor voltammetric determination of flutamide by DC voltammetry (DCV) and differential pulse voltammetry (DPV) at screen-printed carbon electrodes (SPCEs). Under optimum conditions (Britton-Robinson buffer pH 7.0 - methanol (9:1)), linear calibration curves were measure with limits of quantification 6x10(-7) molL(-1) and 8x10(-7) molL(-1) for DCV at SPCEs, respectively. The newly developed methods were successfully applied to the determination of the drug in pharmaceutical formulation Apo-Flutamide (Eulexin tablets). Flutamide, 4-nitro-3-trifluoromethyl-isobutylanilide, is the active component of a synthetic nonsteroidal antiandrogen drug, which is commonly used in the treatment of advanced prostate cancer. In this contribution, optimum conditions have been found vor voltammetric determination of flutamide by DC voltammetry (DCV) and differential pulse voltammetry (DPV) at screen-printed carbon electrodes (SPCEs). Under optimum conditions (Britton-Robinson buffer pH 7.0 - methanol (9:1)), linear calibration curves were measure with limits of quantification 6x10(-7) molL(-1) and 8x10(-7) molL(-1) for DCV at SPCEs, respectively. The newly developed methods were successfully applied to the determination of the drug in pharmaceutical formulation Apo-Flutamide (Eulexin tablets). (en)
Title	Voltammetric determination of anticancer drug flutamide at screen-printed carbon electrodes Voltammetric determination of anticancer drug flutamide at screen-printed carbon electrodes (en)
skos:prefLabel	Voltammetric determination of anticancer drug flutamide at screen-printed carbon electrodes Voltammetric determination of anticancer drug flutamide at screen-printed carbon electrodes (en)
skos:notation	RIV/61388955:_____/11:00359971!RIV12-GA0-61388955
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP206/11/1638), P(IAA400400806), P(LC06035), Z(AV0Z40400503), Z(MSM0021620857)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Navrátil, Tomáš
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav fyzikální chemie J. Heyrovského AV ČR, v.v.i.
http://linked.open...dnocenehoVysledku	239510
http://linked.open...ai/riv/idVysledku	RIV/61388955:_____/11:00359971
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	creatine; screen-printed carbon electrodes; flutamide (en)
http://linked.open.../riv/klicoveSlovo	creatine flutamide screen-printed carbon electrodes
http://linked.open...ontrolniKodProRIV	[79C571F76A37]
http://linked.open...v/mistoKonaniAkce	Jetřichovice
http://linked.open...i/riv/mistoVydani	Ústí nad Labem
http://linked.open...i/riv/nazevZdroje	Sborník přednášek. XXXI. Moderní elektrochemické metody
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Novel electrochemical sensors and sensing techniques for the analysis of nucleic acids structure and interactions Transport of Charged and Uncharged Species across Models of Biological Membranes Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine.
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Barek, J. Navrátil, Tomáš Vyskočil, V.
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2011-05-23 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Struktura, reaktivita a dynamika molekulárních a biomolekulárních systémů: teorie, experiment, aplikace Nové molekulární systémy pro pokročilé aplikace prospěšné pro zdraví a šetrné k životnímu prostředí
number of pages	5 (xsd:int)
http://purl.org/ne...btex#hasPublisher	BEST servis
https://schema.org/isbn	978-80-254-9634-3

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