About: Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells     Goto   Sponge   NotDistinct   Permalink

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  • Abstract- The effects of low-power ultrasound, the anti-cancer drug cisplatin, and their combined application were studied in two lines of human ovarian carcinoma cells, A2780 and A2780cis. Four modes of treatment were used: exposure to ultrasonic field, application of cisplatin, exposure to ultrasound followed by cisplatin, and presence of cisplatin followed by exposure to application ultrasound. Ultrasound was used at intensities of 0.5 W/cm(2) and 1.0 W/cm(2) for 10 min, cisplatin was applied at concentrations of 1 mu M and 6 mu M per cell suspension treated in A2780 and cisplatin-resistant A2780cis cells, respectively. The results of each experimental treatment were assessed by the resultant cell viability related to the viability of control cells, using a standard MTT test. It was shown that a combined effect of ultrasound and cisplatin was more effective than that of ultrasound or cisplatin alone.
  • Abstract- The effects of low-power ultrasound, the anti-cancer drug cisplatin, and their combined application were studied in two lines of human ovarian carcinoma cells, A2780 and A2780cis. Four modes of treatment were used: exposure to ultrasonic field, application of cisplatin, exposure to ultrasound followed by cisplatin, and presence of cisplatin followed by exposure to application ultrasound. Ultrasound was used at intensities of 0.5 W/cm(2) and 1.0 W/cm(2) for 10 min, cisplatin was applied at concentrations of 1 mu M and 6 mu M per cell suspension treated in A2780 and cisplatin-resistant A2780cis cells, respectively. The results of each experimental treatment were assessed by the resultant cell viability related to the viability of control cells, using a standard MTT test. It was shown that a combined effect of ultrasound and cisplatin was more effective than that of ultrasound or cisplatin alone. (en)
Title
  • Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells
  • Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells (en)
skos:prefLabel
  • Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells
  • Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells (en)
skos:notation
  • RIV/00216224:14110/10:00043266!RIV11-GA0-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA305/05/2030), P(LC06077)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 248900
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/10:00043266
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Carcinoma cells; Cisplatin; Ultrasound; Viability; MTT test (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [C9C38D821CBA]
http://linked.open...i/riv/nazevZdroje
  • Ultrasonics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 50
http://linked.open...iv/tvurceVysledku
  • Slaninová, Iva
  • Bernard, Vladan
  • Mornstein, Vojtěch
  • Škorpíková, Jiřina
http://linked.open...ain/vavai/riv/wos
  • 000273954700004
issn
  • 0041-624X
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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