About: Elevated lactate is a reliable marker pointing to mitochondrial disorders even in children after brief seizures.

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About: Elevated lactate is a reliable marker pointing to mitochondrial disorders even in children after brief seizures. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Lactate and alanine concentration measurement is useful first-line tool in assessing children with suspected mitochondrial disorders. : Our data indicate that examination of B- and CSF-lactate levels can be considered as a determinant of mitochondrial disorders, with an ability to distinguish these patients from the epileptic ones. Our results suggest that there is no effect of short-period tonic-clonic seizures on the significant raise of B-and CSF-lactate concentrations. Determination of alanine levels also has a high specificity to distinguish between mitochondrial and other multisystem disorders. Lactate and alanine concentration measurement is useful first-line tool in assessing children with suspected mitochondrial disorders. : Our data indicate that examination of B- and CSF-lactate levels can be considered as a determinant of mitochondrial disorders, with an ability to distinguish these patients from the epileptic ones. Our results suggest that there is no effect of short-period tonic-clonic seizures on the significant raise of B-and CSF-lactate concentrations. Determination of alanine levels also has a high specificity to distinguish between mitochondrial and other multisystem disorders. (en)
Title	Elevated lactate is a reliable marker pointing to mitochondrial disorders even in children after brief seizures. Elevated lactate is a reliable marker pointing to mitochondrial disorders even in children after brief seizures. (en)
skos:prefLabel	Elevated lactate is a reliable marker pointing to mitochondrial disorders even in children after brief seizures. Elevated lactate is a reliable marker pointing to mitochondrial disorders even in children after brief seizures. (en)
skos:notation	RIV/00216208:11310/10:10081988!RIV11-MSM-11310___
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika	Neuveden
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Švandová, Ivana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	256898
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/10:10081988
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	seizures.; brief; after; children; even; disorders; mitochondrial; pointing; marker; reliable; lactate; Elevated (en)
http://linked.open.../riv/klicoveSlovo	disorders Elevated pointing reliable seizures. children marker after brief lactate mitochondrial even
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[0C8DFF789F9C]
http://linked.open...i/riv/nazevZdroje	European Journal of Paediatric Neurology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	2010
http://linked.open...iv/tvurceVysledku	Honzík, Tomáš Ješina, Pavel Magner, Martin Szentiványi, Karol Tesařová, Markéta Zeman, Jiří Švandová, Ivana
http://linked.open...n/vavai/riv/zamer	Molekulární biologie a patologie buňky za normy a u vybraných klinicky závažných patologických procesů
issn	1090-3798
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	11310

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