About: 20alpha-hydroxy-metabolites of neuroactive pregnenolone isomers, progesterone and pregnenolone around parturition and the importace in physiology and diagnostics     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description
  • The project investigates a possibility of influencing of the onset of parturition by changes in activity of 20alfa-hydroxysteroid dehydrogenase, which could contribute to the accelerating catabolism of progesterone and neuroinhibiting pregnanolone isomers near term. The latter substances probably sustain the pregnancy also in human. (en)
  • Projekt studuje možnost ovlivnění nástupu porodu změnami aktivity 20alfa-hydroxysteroidní dehydrogenázy, které by mohly v závěru těhotenství přispívat ke zrychlení katabolismu progesteronu a neuroinhibičních 3alfa-pregnanolonových izomerů zajišťujících pravděpodobně i u člověka udržení těhotenství.
Title
  • 20alpha-hydroxy-metabolites of neuroactive pregnenolone isomers, progesterone and pregnenolone around parturition and the importace in physiology and diagnostics (en)
  • 20alfa-Hydroxy-metabolity neuroaktivních pregnanolonových izomerů, progesteronu a pregnenolonu okolo porodu a jejich význam ve fyziologii a diagnostice
skos:notation
  • NR9156
http://linked.open...avai/cep/aktivita
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http://linked.open.../cep/klicovaSlova
  • pregnandiols; pregnanolone isomers; neuroactive steroids; parturition; steroid conjugates; ionotropic receptors; serum; GC-MS (en)
http://linked.open...ep/partnetrHlavni
http://linked.open...inujicichPrijemcu
http://linked.open...cep/pocetPrijemcu
http://linked.open...ocetSpoluPrijemcu
http://linked.open.../pocetVysledkuRIV
http://linked.open...enychVysledkuVRIV
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  • Cíle anotovaného projektu byly splněnys velmi dobrými výsledky, publikovány 1x v časopise s IF 3,056, další práce byla publikována ve stejném časopise s dedikací IGA MZ ČR NR9156 (cs)
  • The targets of the project were fulfilled and the result were published 1x in journal with IF 3,056, further simillar paper was accept to the same journal with dedication to IGA MZ CR with another number (NR9146-3) (en)
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • ionotropic receptors
  • neuroactive steroids
  • parturition
  • pregnanolone isomers
  • serum
  • steroid conjugates
  • pregnandiols
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