About: Transcription factor microphthalmia as a regulator of cell differentiation in malignant melanocytes     Goto   Sponge   NotDistinct   Permalink

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Description
  • We propose to study mechanismus of transcription activation by microphthalmia (MITF) in normal and malignant melanocytes, the role of MITF in oncogenic transformation, and functional significance of its inteeraction with the retinoblastoma protein. (en)
  • Bude studován mechanismus aktivace transkripce faktorem microphthalmia (MITF) v normálních i nádorových melanocytech, vztah MITF k nádorové transformaci melanocytů a funkční význam interakce MITF s retinoblastoma proteinem.
Title
  • Transcription factor microphthalmia as a regulator of cell differentiation in malignant melanocytes (en)
  • Transkripční faktor microphthalmia jako regulátor buněčné diferenciace maligně transformovaných melanocytů
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  • NC6804
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  • Differentiation;transcription;MITF;melanocytes;Markers;malignant melanoma;Rb protein;microphthalmia (en)
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  • Prioritní poznatky o regulaci diferenciace melanocytů. (cs)
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  • Differentiation
  • malignant melanoma
  • transcription
  • MITF
  • Markers
  • melanocytes
  • Rb protein
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