Spatial cognition (orientation, navigation) belongs to the most intensively investigated topics in neuroscientific disciplines. The present project is focused on the studies of neural substrate of specific components of orientation in rodents, with the usage of lesion, inactivation and pharmacological techniques and behavioral tests in both stable and dynamic environmental conditions. Another part of the project is represented by investigation of cognitive processes of rhesus monkeys (Macaca mulatta) in non-invasive experiments by means of computer screen and operant conditioning. The project also involves the study of mechanisms of allocentric and egocentric orientation in human healthy volunteers and elderly subjects in the real and virtual spatial navigation tests. Results of the present project will enrich our knowledge about mechanisms of spatial cognition in various animal species including humans and specific components of cognition. (en)
Studium nervového substrátu prostorové kognice hlodavců pomocí lézí, inaktivací a farmakologických metod. Studium kognice opic makaků s pomocí kognitivních úloh za použití počítačového monitoru. Zkoumání orientace lidí ve stabilním a dynamickém prostředí pomocí reálných a virtuálních testů.