About: Development of new transgenic technologies for biomedical research and pharmaceutical industry

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description	Cílem projektu je vyvinout a optimalizovat technologii transgeneze s transpozonovými vektory Sleeping Beauty a s využitím RMCE (recombinase mediated cassette exchange) metody u laboratorního potkana. Aplikovat tuto vysoce efektívní technologii a vyprodukovat transgenní potkany, modely specifických lidských chorob, které budou komerčně využitelné prostřednictvím firmy Velaz, s.r.o. ve výzkumných organizacích biomedicínského zaměření nebo ve farmaceutických firmách. (cs) The aims of the project are (1) to develop and optimize technologies for transgenesis of the laboratory rat with transposon system Sleeping Beauty and highly effective SB100X transposase and develop RMCE (recombinase mediated cassette exchange) technique for in vivo use, (2) to adopt these technologies to produce transgenic rats, models of human diseases, and (3) make new models commercially available for biomedical research and pharmaceutical industry. (en)
Title	Vývoj nových technologií transgeneze pro biomedicínský výzkum a farmaceutický průmysl (cs) Development of new transgenic technologies for biomedical research and pharmaceutical industry (en)
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http://linked.open...vai/klicova-slova	transgenic- transposon- Sleeping Beauty- RMCE- rat- models of human diseases (en)
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