About: The effect of histone deacetylase inhibitors on TEL/AML1

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About: The effect of histone deacetylase inhibitors on TEL/AML1 - positive leukaemic cells Goto Sponge NotDistinct Permalink

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Description	Using histone deacetylase inhibitors, we will study chromatin remodelling leading to apoptosis and differentiation of TEL/AML1-positive leukaemic cells. We will analyse in vitro effect of this therapy on the changes of cell cycle and the gene expression in leukaemic cells. (en) Pomocí inhibitorů deacetylas histonů způsobíme remodelaci chromatinu vedoucí k apoptose a diferenciaci TEL/AML1 positivních leukemických buněk. Budeme in vitro analysovat vliv této léčby na změny buněčného cyklu a genové exprese v leukemických buňkách. (cs)
Title	Vliv inhibitorů deacetylas histonů na TEL/AML1 positivní leukemické buňky (cs) The effect of histone deacetylase inhibitors on TEL/AML1 - positive leukaemic cells (en)
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http://linked.open...vai/klicova-slova	Childhood acute leukaemias; TEL/AML1; histone deacetylase inhibitors; chromatin; remodelling (en)
http://linked.open...avai/konec-reseni	2007-12-31 (xsd:date)
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is http://linked.open...ain/vavai/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2005/NR8316/orjk-11130 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2006/NR8316/orjk-11130 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2007/NR8316/orjk-11130 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2008/NR8316/orjk-11130

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