About: Can administration of corticosteroids lead to structural changes in hippocampus? Prospective MRI study in human patients treated with high doses of corticosteroids.

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About: Can administration of corticosteroids lead to structural changes in hippocampus? Prospective MRI study in human patients treated with high doses of corticosteroids. Goto Sponge NotDistinct Permalink

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Description	Using the MRI volumetry, neuropsychological assessment and endocrinological screening, we will elucidate the relationship between long term treatment with corticosteroids and structural and functional changes of hippocampus. 20 subjects (power -95%) starting the treatment with corticosteroids will be studied by within subject design paradigm. (en) Pomocí MRI volumetrie, neuropsychologických testů a endokrinologického vyšetření objasníme vztah mezi dlouhodobou léčbou kortikoidy a strukturálními a funkčními změnami hipokampu. Půjde o longitudinální sledování skupiny 20 pacientů (power - 95%) u nichž se začíná s léčbou kortikoidy. (cs)
Title	Působí exogenně podávané kortikoidy strukturální změny hipokampu? Longitudiální studie s využitím MRI volumetrie u pacientů užívajících kortikoidy (cs) Can administration of corticosteroids lead to structural changes in hippocampus? Prospective MRI study in human patients treated with high doses of corticosteroids. (en)
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