About: Lupus nephritis - efficacious immunosuppressive therapy and long-term survival prospects

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Description	Posti×enÝ ledvin u SLE znamenß stßle Üpatnou prognˇzu pro ×ivot nemocnÚho.+Ŕinnou lÚŔbu p°edstavuje podßvßnÝ cyklofosfamidu nebo cyklosporinu,studovanÚ v rßmci grantu IGA MZ +R 2148-3,kterÚ p°ineslo vřznamnÚ originßlnÝ vřsledky. CÝlem navrhovanÚ studie v p°ÝmÚ nßvaznosti na shora uvedenÚ vřsledky je zhodnotit v delÜÝm ŔasovÚm odstupu trvßnÝ p°ÝznivÚho lÚŔebnÚho efektu, vřskyt ne×ßdoucÝch toxickřch projev¨ vŔetný malignity a pozitivnÝ ovlivnýnÝ prognˇzy nemocnÚho. (cs) Renal damage in SLE still remains a sign of bad prognosis for a patients life.Efficacious therapy represented by the application of CFM or cyslosporine was studied in previous trial (IGA MZd +R No.2148-3). This study brought significant ond convincing results. The aim of the new study,seen as uninterrupted continuation of the preivous trial,is to evaluate in 5 years interval the duration of therapeutic effect and to asses the incidence of undesired toxic events incl. malignancy and positive influence upon the life prognosis. (en)
Title	Lupus nephritis - efficacious immunosuppressive therapy and long-term survival prospects (en) Lupoidní nefritída - účinné imunosupresivní léčení a prognóza onemocnění (cs)
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is http://linked.open...ain/vavai/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/1997/IZ4356/ico-00023728 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/1997/IZ4356/ico-00064165 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/1998/IZ4356/ico-00023728 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/1999/IZ4356/ico-00023728

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