About: Instability of the genome of bone marrow cells of patients with AML and MDS.     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Zjistit nenáhodnost vstupu chromosomů do přestaveb a rekurenci zlomových míst. Identifikovat geny spolupůsobící při progresi malignity a geny v oblastech s delecemi, zejména na chromosomu 5. Definovat skupiny pacientů vhodné pro individuální léčbu. (cs)
  • The aim of our study in cooperation with COST projecBM0801 is to analyse chromosomal changes in complex karyotypes of patients with MDS and AML in detail using all molecular cytogenetic techniques which are available and to search for the new, so far non-described recurrent chromosomal changes. We wish to define the frequency and significance of these aberrations for disease progression and transformation of MDS into AML. As many rearrangements are cryptic and therefore their identification is possible by molecular-cytogenetic methods only, we will exploit modifications of FISH methods routinely used in our Center of Oncocytogenetics (FISH, I-FISH. mFISH, mBAND, CGH) and as the new approach we will start to use array CGH analyses. We will start pilot study with the specially designed chip for array CGH analyses of chromosome 5. We will also continue to search for rearrangments of MLL gene in myeloid malignancies to establish prognostic values in our cohort. We have very close co-operation with clin (en)
Title
  • Nestabilita genomu buněk kostní dřeně nemocných s MDS a AML (cs)
  • Instability of the genome of bone marrow cells of patients with AML and MDS. (en)
http://linked.open...vai/cislo-smlouvy
http://linked.open...avai/druh-souteze
http://linked.open...domain/vavai/faze
http://linked.open...vavai/hlavni-obor
http://linked.open...vai/vedlejsi-obor
http://linked.open...vavai/id-aktivity
http://linked.open.../vavai/id-souteze
http://linked.open...n/vavai/kategorie
http://linked.open...vai/klicova-slova
  • genome instability in malignant cells chromosomal aberrations molecular cytogenetics myelodysplastic syndromes (MDS) acute myeloid leukemia (AML) (en)
http://linked.open...avai/konec-reseni
http://linked.open...nujicich-prijemcu
http://linked.open...avai/poskytovatel
http://linked.open...avai/start-reseni
http://linked.open...ai/statni-podpora
http://linked.open...vavai/typProjektu
http://linked.open...ai/uznane-naklady
http://linked.open...ai/pocet-prijemcu
http://linked.open...cet-spoluprijemcu
http://linked.open...ai/pocet-vysledku
http://linked.open...ku-zverejnovanych
is http://linked.open...ain/vavai/projekt of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 47 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software