About: Mechanism of antitumor activity of metallodrugs. DNA replication and repair of DNA damage

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About: Mechanism of antitumor activity of metallodrugs. DNA replication and repair of DNA damage Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description	To obtain data that will substantially extent the theoretical background needed for design, development and synthesis of novel anticancer metal-based drugs and in this way improve relationships between structure and pharmacological activity of this class of compounds. More specifically, to obtain data on mechanisms underlying replication and repair of DNA damaged by antitumor transition metal-based compounds. (en) Získat poznatky o klíčových molekulárních mechanismech protinádorových účinků komplexů přechodných kovů. Tyto poznatky využít k rozšíření teoretického zázemí nutného pro vývoj nových, účinnějších metalofarmak vhodných pro léčení rakoviny. (cs)
Title	Mechanism of antitumor activity of metallodrugs. DNA replication and repair of DNA damage (en) Mechanismus účinku protinádorově účinných metalofarmak. Replikace DNA a oprava poškození DNA (cs)
http://linked.open...vai/cislo-smlouvy	http://linked.opendata.cz/resource/domain/vavai/cep/smlouva/1147/2010-32
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http://linked.open...vai/klicova-slova	Antitumor activity; antitumor drugs; DNA; transition metals (en)
http://linked.open...avai/konec-reseni	2011-07-31 (xsd:date)
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is http://linked.open...ain/vavai/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2009/OC09018/orjk-15310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2010/OC09018/orjk-15310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2011/OC09018/orjk-15310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2012/OC09018/orjk-15310

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