About: Pleiotropic effect of hypolipidemics

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
Description	The aim of the project is to get an information whether a model fibrate (fenofibrate) is able to influence significantly the expression and activity of rat liver microsomal cytochrome P450 CYP2C11 and whether this change is also reflected in elevated plasma levels of another concomitantly administered drug (diclofenac) metabolized by the same enzyme. The result may be important for evaluation of drug interactions of fibrates. (en) Cílem je získat informaci, zda modelový fibrát (fenofibrát) významně ovlivní u potkana expresi jednoho z cytochromů P450 (CYP2C11) a zda je toto ovlivnění významné pro hladiny současně podávaného jiného modelového léčiva (diklofenaku). (cs)
Title	Pleiotropic effect of hypolipidemics (en) Pleiotropní účinky hypolipidemik (cs)
http://linked.open...vai/cislo-smlouvy	http://linked.opendata.cz/resource/domain/vavai/cep/smlouva/1682/2009-32 z
http://linked.open...lsi-vedlejsi-obor	http://linked.opendata.cz/resource/domain/vavai/cep/obor/ED
http://linked.open...avai/druh-souteze	http://linked.opendata.cz/resource/domain/vavai/cep/druh-souteze/VS
http://linked.open...domain/vavai/faze	http://linked.opendata.cz/resource/domain/vavai/cep/faze/37049441
http://linked.open...vavai/hlavni-obor	http://linked.opendata.cz/resource/domain/vavai/cep/obor/FR
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http://linked.open.../vavai/id-souteze	http://linked.opendata.cz/resource/domain/vavai/cep/soutez/SMSM2009OC4
http://linked.open...n/vavai/kategorie	http://linked.opendata.cz/resource/domain/vavai/cep/kategorie/1
http://linked.open...vai/klicova-slova	fenofibrate; cytochrome P450; CYP2C11; CYP2C9; diclofenac (en)
http://linked.open...avai/konec-reseni	2009-05-31 (xsd:date)
http://linked.open...nujicich-prijemcu	0 (xsd:integer)
http://linked.open...avai/poskytovatel	http://linked.opendata.cz/resource/domain/vavai/cep/poskytovatel/MSM
http://linked.open...avai/start-reseni	2009-04-01 (xsd:date)
http://linked.open...ai/statni-podpora	350 (xsd:integer)
http://linked.open...vavai/typProjektu	http://linked.opendata.cz/resource/domain/vavai/cep/typ/P
http://linked.open...ai/uznane-naklady	350 (xsd:integer)
http://linked.open...ai/pocet-prijemcu	1 (xsd:integer)
http://linked.open...cet-spoluprijemcu	0 (xsd:integer)
http://linked.open...ai/pocet-vysledku	1 (xsd:integer)
http://linked.open...ku-zverejnovanych	1 (xsd:integer)
is http://linked.open...ain/vavai/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2009/OC09004/orjk-15110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2010/OC09004/orjk-15110

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