About: Nanomechanics and electrostatics of interactions of implants with living tissue

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description	Osteoarthritis affects hundreds of millions of patients throughout the world, causing debilitating pain, loss of mobility and eventually severe disability. This has a great impact on individuals and on society as a whole. It was shown in our previous studies, that excessive mechanical loading of joint may initiate its degeneration. Though joint replacement surgery can relieve pain dramatically and improve mobility, it is not always a permanent solution. Implant loosening can result in the need for revision surgery. (en) Osteartróza postihuje milióny pacientů na celém světě a způsobuje omezení pohybu s bolestí. Tato nemoc má velký dopad na jednotlivca ale také na celou společnost. Komplikace při náhradách kloubů mohou být způsobeny mechanolelektrickou interakcí mezi implantátem a kostí ale také reakcí těla na produkty otěru polyetylénu. Cílem projektu objasnit fyzikální mechanizmy vedoucí k uvolnění endoprotézy, zejména roli interakce záporně nabité embrány osteoblastů a titanového povrchu. (cs)
Title	Nanomechanics and electrostatics of interactions of implants with living tissue (en) Nanomechanika a elektrostatika interakcí mezi implantáty a živými tkáněmi (cs)
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http://linked.open...vai/klicova-slova	Biomechanics; Implants Loosening; Wear (en)
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